Bactericidal/permeability-increasing protein inhibits growth of a strain of Acholeplasma laidlawii and L forms of the gram-positive bacteria Staphylococcus aureus and Streptococcus pyogenes

被引：17

作者：

Horwitz, AH ^{[1
]}

Williams, RE ^{[1
]}

Liu, PS ^{[1
]}

Nadell, R ^{[1
]}

机构：

[1] LLC, XOMA US, Santa Monica, CA 90404 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1999年 / 43卷 / 09期

关键词：

D O I：

10.1128/AAC.43.9.2314

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Bactericidal/permeability-increasing protein (BPI) inhibited growth of cell wall-deficient Acholeplasma laidlawii and L forms of certain strains of Staphylococcus aureus and Streptococcus pyogenes. However, the same strains of S. aureus and S. pyogenes with intact cell walls were not susceptible to the growth-inhibitory effects of BPI.

引用

收藏

页码：2314 / 2316

页数：3

相关论文

共 10 条

[1]

[Anonymous], 1992, INFLAMMATION BASIC P

[2] THE BACTERICIDAL PERMEABILITY-INCREASING PROTEIN (BPI), A POTENT ELEMENT IN HOST-DEFENSE AGAINST GRAM-NEGATIVE BACTERIA AND LIPOPOLYSACCHARIDE [J].

ELSBACH, P ;

WEISS, J .

IMMUNOBIOLOGY, 1993, 187 (3-5) :417-429

[3] HIGH-AFFINITY BINDING OF THE BACTERICIDAL PERMEABILITY-INCREASING PROTEIN AND A RECOMBINANT AMINO-TERMINAL FRAGMENT TO THE LIPID-A REGION OF LIPOPOLYSACCHARIDE [J].

GAZZANOSANTORO, H ;

PARENT, JB ;

GRINNA, L ;

HORWITZ, A ;

PARSONS, T ;

THEOFAN, G ;

ELSBACH, P ;

WEISS, J ;

CONLON, PJ .

INFECTION AND IMMUNITY, 1992, 60 (11) :4754-4761

[4] HUMAN LIPOPOLYSACCHARIDE-BINDING PROTEIN POTENTIATES BACTERICIDAL ACTIVITY OF HUMAN BACTERICIDAL PERMEABILITY-INCREASING PROTEIN [J].

HORWITZ, AH ;

WILLIAMS, RE ;

NOWAKOWSKI, G .

INFECTION AND IMMUNITY, 1995, 63 (02) :522-527

[5] Expression and characterization of cysteine-modified variants of an amino-terminal fragment of bactericidal/permeability-increasing protein [J].

Horwitz, AH ;

Leigh, SD ;

Abrahamson, S ;

GazzanoSantoro, H ;

Liu, PS ;

Williams, RE ;

Carroll, SF ;

Theofan, G .

PROTEIN EXPRESSION AND PURIFICATION, 1996, 8 (01) :28-40

[6]

Kenny GE, 1991, MANUAL CLIN MICROBIO, P478

[7]

MADOFF S, 1986, BACTERIAL L FORMS, P1

[8] SEPARATION OF SUBLETHAL AND LETHAL EFFECTS OF THE BACTERICIDAL PERMEABILITY INCREASING PROTEIN ON ESCHERICHIA-COLI [J].

MANNION, BA ;

WEISS, J ;

ELSBACH, P .

JOURNAL OF CLINICAL INVESTIGATION, 1990, 85 (03) :853-860

[9] EFFECTS OF THE BACTERICIDAL PERMEABILITY-INCREASING PROTEIN OF POLYMORPHONUCLEAR LEUKOCYTES ON ISOLATED BACTERIAL CYTOPLASMIC MEMBRANE-VESICLES [J].

VELD, GI ;

MANNION, B ;

WEISS, J ;

ELSBACH, P .

INFECTION AND IMMUNITY, 1988, 56 (05) :1203-1208

[10] HUMAN BACTERICIDAL PERMEABILITY-INCREASING PROTEIN AND A RECOMBINANT NH2-TERMINAL FRAGMENT CAUSE KILLING OF SERUM-RESISTANT GRAM-NEGATIVE BACTERIA IN WHOLE-BLOOD AND INHIBIT TUMOR-NECROSIS-FACTOR RELEASE INDUCED BY THE BACTERIA [J].

WEISS, J ;

ELSBACH, P ;

SHU, C ;

CASTILLO, J ;

GRINNA, L ;

HORWITZ, A ;

THEOFAN, G .

JOURNAL OF CLINICAL INVESTIGATION, 1992, 90 (03) :1122-1130