Clinical Predictors of Aggressive/Disabling Disease: Ulcerative Colitis and Crohn Disease

被引:28
作者
Blonski, Wojciech [1 ,2 ]
Buchner, Anna M. [1 ]
Lichtenstein, Gary R. [1 ]
机构
[1] Univ Penn, Perelman Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USA
[2] Med Univ, Dept Gastroenterol, PL-50556 Wroclaw, Poland
关键词
Clinical predictors; Ulcerative colitis; Crohn disease; Inflammatory bowel disease; Aggressive disease; INFLAMMATORY-BOWEL-DISEASE; PRIMARY SCLEROSING CHOLANGITIS; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; POPULATION-BASED COHORT; GLUCOCORTICOSTEROID TREATMENT FAILURE; CAUSE-SPECIFIC MORTALITY; NATURAL-HISTORY; MAGNIFYING COLONOSCOPY; VIENNA CLASSIFICATION; INCEPTION COHORT;
D O I
10.1016/j.gtc.2012.01.008
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
Inflammatory bowel disease is classically characterized by periods of remission and clinical relapse. In some patients, disease may take an aggressive course that involves frequent relapses, continued active disease, intensified medical treatment, or even a surgical approach. It is important to determine clinical factors that predict the aggressive course of disease to implement appropriate therapy to prevent patients from developing complications and to improve their quality of life. This review discusses clinical factors that have been suggested to predict an aggressive course of disease in patients with ulcerative colitis and Crohn disease.
引用
收藏
页码:443 / +
页数:21
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