Clinical Predictors of Aggressive/Disabling Disease: Ulcerative Colitis and Crohn Disease
被引:28
作者:
Blonski, Wojciech
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机构:
Univ Penn, Perelman Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USA
Med Univ, Dept Gastroenterol, PL-50556 Wroclaw, PolandUniv Penn, Perelman Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USA
Blonski, Wojciech
[1
,2
]
Buchner, Anna M.
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机构:
Univ Penn, Perelman Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USAUniv Penn, Perelman Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USA
Buchner, Anna M.
[1
]
Lichtenstein, Gary R.
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机构:
Univ Penn, Perelman Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USAUniv Penn, Perelman Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USA
Lichtenstein, Gary R.
[1
]
机构:
[1] Univ Penn, Perelman Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USA
[2] Med Univ, Dept Gastroenterol, PL-50556 Wroclaw, Poland
Inflammatory bowel disease is classically characterized by periods of remission and clinical relapse. In some patients, disease may take an aggressive course that involves frequent relapses, continued active disease, intensified medical treatment, or even a surgical approach. It is important to determine clinical factors that predict the aggressive course of disease to implement appropriate therapy to prevent patients from developing complications and to improve their quality of life. This review discusses clinical factors that have been suggested to predict an aggressive course of disease in patients with ulcerative colitis and Crohn disease.