Directed DNA metallization

被引：252

作者：

Burley, GA

Gierlich, J

Mofid, MR

Nir, H

Tal, S

Eichen, Y

Carell, T ^{[1
]}

机构：

[1] Technion Israel Inst Technol, Dept Chem, Haifa, Israel

[2] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 05期

关键词：

D O I：

10.1021/ja055517v

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Genes of interest can be selectively metallized via the incorporation of modified triphosphates. These triphosphates bear functions that can be further derivatized with aldehyde groups via the use of click chemistry. Treatment of the aldehyde-labeled gene mixture with the Tollens reagent, followed by a development process, results in the selective metallization of the gene of interest in the presence of natural DNA strands. Copyright © 2006 American Chemical Society.

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页码：1398 / 1399

页数：2

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