An assessment of statin safety by muscle experts

被引:201
作者
Thompson, PD
Clarkson, PM
Rosenson, RS
机构
[1] Hartford Hosp, Div Cardiol, Hartford, CT 06102 USA
[2] Univ Massachusetts, Amherst, MA 01003 USA
[3] Northwestern Univ, Chicago, IL 60611 USA
关键词
D O I
10.1016/j.amjcard.2005.12.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The National Lipid Association's (NLA) Muscle Safety Expert Panel was charged with the duty of examining the definitions, causative factors, and management of statin myopathy. The Panel was asked to use its evidence-based findings to form recommendations in response to a series of specific questions posed by the Task Force. The panel was composed of a clinical cardiologist, an exercise physiologist and skeletal muscle expert, and an expert in preventive cardiology who also examined skeletal muscle complications of statin use. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码:69C / 76C
页数:8
相关论文
共 42 条
[1]  
[Anonymous], 2003, LANCET, V362, P1341
[2]   Risk for myopathy with statin therapy in high-risk patients [J].
Ballantyne, CM ;
Corsini, A ;
Davidson, MH ;
Holdaas, H ;
Jacobson, TA ;
Leitersdorf, E ;
März, W ;
Reckless, JPD ;
Stein, EA .
ARCHIVES OF INTERNAL MEDICINE, 2003, 163 (05) :553-564
[3]   RACIAL-DIFFERENCES IN SERUM CREATINE-KINASE LEVELS [J].
BLACK, HR ;
QUALLICH, H ;
GARELECK, CB .
AMERICAN JOURNAL OF MEDICINE, 1986, 81 (03) :479-487
[4]  
Clarkson PM, 2002, AM J PHYS MED REHAB, V81, pS52, DOI [10.1097/00002060-200211001-00007, 10.1097/01.PHM.0000029772.45258.43]
[5]  
CLARKSON PM, IN PRESS MED SCI SPO
[6]   Food-drug interaction: grapefruit juice augments drug bioavailability - mechanism, extent and relevance [J].
Dahan, A ;
Altman, H .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2004, 58 (01) :1-9
[7]   The efficacy and six-week tolerability of Simvastatin 80 and 160 mg/day [J].
Davidson, MH ;
Stein, EA ;
Dujovne, CA ;
Hunninghake, DB ;
Weiss, SR ;
Knopp, RH ;
Illingworth, DR ;
Mitchel, YB ;
Melino, MR ;
Zupkis, RV ;
Dobrinska, MR ;
Amin, RD ;
Tobert, JA .
AMERICAN JOURNAL OF CARDIOLOGY, 1997, 79 (01) :38-42
[8]   Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes - Phase Z of the A to Z trial [J].
de Lemos, JA ;
Blazing, MA ;
Wiviott, SD ;
Lewis, EF ;
Fox, KAA ;
White, HD ;
Rouleau, JL ;
Pedersen, TR ;
Gardner, LH ;
Mukherjee, R ;
Ramsey, KE ;
Palmisano, J ;
Bilheimer, DW ;
Pfeffer, MA ;
Califf, RM ;
Braunwald, E .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (11) :1307-1316
[9]  
EAST C, 1988, NEW ENGL J MED, V318, P47
[10]   Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro [J].
Flint, OP ;
Masters, BA ;
Gregg, RE ;
Durham, SK .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1997, 145 (01) :91-98