The aspartic acid metabolic pathway, an exciting and essential pathway in plants

被引:217
作者
Azevedo, RA
Lancien, M
Lea, PJ
机构
[1] Univ Sao Paulo, Escola Super Agr Luiz Queiroz, Dept Genet, BR-13400970 Piracicaba, SP, Brazil
[2] Univ Lancaster, Dept Biol Sci, Lancaster, England
关键词
aspartic acid; asparagine; isoleucine; lysine; methionine; threonine;
D O I
10.1007/s00726-005-0245-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Aspartate is the common precursor of the essential amino acids lysine, threonine, methionine and isoleucine in higher plants. In addition, aspartate may also be converted to asparagine, in a potentially competing reaction. The latest information on the properties of the enzymes involved in the pathways and the genes that encode them is described. An understanding of the overall regulatory control of the flux through the pathways is undisputedly of great interest, since the nutritive value of all cereal and legume crops is reduced due to low concentrations of at least one of the aspartate-derived amino acids. We have reviewed the recent literature and discussed in this paper possible methods by which the concentrations of the limiting amino acids may be increased in the seeds.
引用
收藏
页码:143 / 162
页数:20
相关论文
共 195 条
  • [1] THREONINE-SENSITIVE ASPARTATE KINASE AND HOMOSERINE DEHYDROGENASE FROM PISUM-SATIVUM
    AARNES, H
    ROGNES, SE
    [J]. PHYTOCHEMISTRY, 1974, 13 (12) : 2717 - 2724
  • [2] Can genetic manipulation of plant nitrogen assimilation enzymes result in increased crop yield and greater N-use efficiency? An assessment
    Andrews, M
    Lea, PJ
    Raven, JA
    Lindsey, K
    [J]. ANNALS OF APPLIED BIOLOGY, 2004, 145 (01) : 25 - 40
  • [3] [Anonymous], 1999, Plant amino acids: biochemistry and biotechnology
  • [4] Regulation of lysine catabolism in higher plants
    Arruda, P
    Kemper, EL
    Papes, F
    Leite, A
    [J]. TRENDS IN PLANT SCIENCE, 2000, 5 (08) : 324 - 330
  • [5] Enhanced levels of methionine and cysteine in transgenic alfalfa (Medicago sativa L.) plants over-expressing the Arabidopsis cystathionine γ-synthase gene
    Avraham, T
    Badani, H
    Galili, S
    Amir, R
    [J]. PLANT BIOTECHNOLOGY JOURNAL, 2005, 3 (01) : 71 - 79
  • [6] Regulation of lysine metabolism and endosperm protein synthesis by the opaque-5 and opaque-7 maize mutations
    Azevedo, RA
    Lea, PJ
    Damerval, C
    Landry, J
    Bellato, CM
    Meinhardt, LW
    Le Guilloux, M
    Delhaye, S
    Varisi, VA
    Gaziola, SA
    Gratao, PL
    Toro, AA
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (15) : 4865 - 4871
  • [7] Genetic control of lysine metabolism in maize endosperm mutants
    Azevedo, RA
    Damerval, C
    Lea, PJ
    Landry, J
    Bellato, CM
    Meinhardt, LW
    Le Guilloux, M
    Delhaye, S
    Toro, AA
    Gaziola, SA
    Varisi, VA
    Gratao, PL
    [J]. FUNCTIONAL PLANT BIOLOGY, 2004, 31 (04) : 339 - 348
  • [8] Regulation of maize lysine metabolism and endosperm protein synthesis by opaque and floury mutations
    Azevedo, RA
    Damerval, C
    Landry, J
    Lea, PJ
    Bellato, CM
    Meinhardt, LW
    Le Guilloux, M
    Delhaye, S
    Toro, AA
    Gaziola, SA
    Berdejo, BDA
    [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 2003, 270 (24): : 4898 - 4908
  • [9] Analysis of the aspartic acid metabolic pathway using mutant genes
    Azevedo, RA
    [J]. AMINO ACIDS, 2002, 22 (03) : 217 - 230
  • [10] Lysine metabolism in higher plants
    Azevedo, RA
    Lea, PJ
    [J]. AMINO ACIDS, 2001, 20 (03) : 261 - 279