What a privilege to reside at the synapse: NMDA receptor signaling to CREB

被引:29
作者
Riccio, A [1 ]
Ginty, DD [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Howard Hughes Med Inst, Dept Neurosci, Baltimore, MD 21205 USA
关键词
D O I
10.1038/nn0502-389
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
NMDA receptors are important for both normal transmission and pathological damage. New results indicate that receptor location makes the key difference: survival-promoting signals derive from synaptic receptors, whereas a cell-death signal comes from extrasynaptic receptors.
引用
收藏
页码:389 / 390
页数:2
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