Periapical replacement resorption of permanent, vital, endodontically treated incisors after orthodontic movement: Report of two cases

Radiographic observations show that periapical replacement resorption (PARR) is a frequent and unpredictable sequella of orthodontic movement of permanent maxillary incisors, Only the apical root portion undergoes resorption, and it is subsequently replaced with normal bone, PARR also occurs without orthodontic tooth movement, but these resorptions differ as to type and location, PARR clearly occurs in teeth with vital pulps after orthodontic movement; however, our two cases and a review of 43 other cases indicate that endodontically treated incisors show a statistically significant lesser frequency and severity of apical resorption than untreated teeth, The role the vital pulp plays in this apical resorption is yet to be determined, A hypothetical explanation is offered suggesting that pulpal neuropeptides may be involved in PARR in both vital and endodontically treated incisors, The role calcium hydroxide plays in endodontically treated teeth is also considered.