Effect of shear stress on cultivation of Bacillus thuringiensis for thuringiensin production

被引：28

作者：

Wu, WT ^{[1
]}

Hsu, YL ^{[1
]}

Ko, YF ^{[1
]}

Yao, LL ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem Engn, Hsinchu 30043, Taiwan

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2002年 / 58卷 / 02期

关键词：

D O I：

10.1007/s00253-001-0827-1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Cultivation of Bacillus thuringiensis for thuringiensin production is a mixed-growth-associated system. Cultivation conditions should be different during the cell growth stage and production stage. In this study, agitation speed and aeration rate were varied during the exponential growth phase and stationary phase in order to investigate the effect of shear stress via agitation on cultivation of B. thuringiensis for thuringiensin production. It was found that shear stress had a significant effect on thuringiensin production during the stationary phase. By decreasing the agitation speed during the stationary phase, product formation was increased up to 43%.

引用

页码：175 / 177

页数：3

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