A Simple Cytosine to G-Clamp Nucleobase Substitution Enables Chiral γ-PNAs to Invade Mixed-Sequence Double-Helical B-form DNA

被引:52
作者
Chenna, Venugopal [1 ]
Rapireddy, Srinivas [1 ]
Sahu, Bichismita [1 ]
Ausin, Cristina [2 ]
Pedroso, Enrique [2 ]
Ly, Danith H. [1 ]
机构
[1] Carnegie Mellon Univ, Dept Chem, Pittsburgh, PA 15213 USA
[2] Univ Barcelona, Dept Quim Organ IBUB, E-08028 Barcelona, Spain
基金
美国国家卫生研究院;
关键词
chiral gamma-PNA; DNA recognition; DNA strand invasion; helical PNA; nucleic acids;
D O I
10.1002/cbic.200800441
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:2388 / 2391
页数:4
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