Aging and muscle loss

被引：37

作者：

Bross, R

Storer, T

Bhasin, S

机构：

[1] Charles R Drew Univ Med & Sci, Los Angeles, CA 90049 USA

[2] El Camino Coll, Torrance, CA 90502 USA

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1999年 / 10卷 / 05期

关键词：

D O I：

10.1016/S1043-2760(98)00143-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aging is associated with a decrease in fat-free mass, an increase in fat mass, and progressive impairment of muscle function and performance. Diminishing anabolic hormone levels and progressive declines in muscle protein turnover contribute to the multifactorial pathophysiology of age-associated sarcopenia. The potential effects of anabolic hormone replacement on body composition and functional capacity are only beginning to be studied.

引用

页码：194 / 198

页数：5

共 62 条

[1] BALGOPAL P, 1997, AM J PHYSIOL, V273, pE790
[2] LEG EXTENSOR POWER AND FUNCTIONAL PERFORMANCE IN VERY OLD MEN AND WOMEN
BASSEY, EJ
FIATARONE, MA
ONEILL, EF
KELLY, M
EVANS, WJ
LIPSITZ, LA
[J]. CLINICAL SCIENCE, 1992, 82 (03) : 321 - 327
[3] Emerging issues in androgen replacement therapy
Bhasin, S
Bremner, WJ
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (01) : 3 - 8
[4] BROZEK J, 1952, FED PROC, V11, P784
[5] Growth hormone (GH)-deficient men are more responsive to GH replacement therapy than women
Burman, P
Johansson, AG
Siegbahn, A
Vessby, B
Karlsson, FA
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (02) : 550 - 555
[6] CARPAS E, 1993, ENDOCR REV, V14, P20
[7] COHN SH, 1985, J LAB CLIN MED, V105, P305
[8] CLINICAL ASPECTS OF GROWTH-HORMONE DEFICIENCY IN ADULTS
DEBOER, H
BLOK, GJ
VANDERVEEN, EA
[J]. ENDOCRINE REVIEWS, 1995, 16 (01) : 63 - 86
[9] EVANS WJ, 1995, J GERONTOL A-BIOL, V50, P147
[10] FEHLING P C, 1992, Medicine and Science in Sports and Exercise, V24, pS11, DOI 10.1249/00005768-199205001-00067

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