Genome-based structural biology

被引：13

作者：

Frishman, D ^{[1
]}

Mewes, HW ^{[1
]}

机构：

[1] Max Planck Inst Biochem, GSF Forschungszentrum Umwelt & Gesundheit, Munich Informat Ctr Prot Sequences, D-82152 Martinsried, Germany

来源：

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY | 1999年 / 72卷 / 01期

关键词：

D O I：

10.1016/S0079-6107(98)00057-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Spectacular achievements in whole genome sequencing open up new possibilities for structural research. Protein structures can now be studied in their natural genomic context. On the other hand, structure prediction algorithms can be improved using species-specific tendencies in folding patterns. Finally, efficient strategies to select targets for structure determination can be devised. In this revew we consider new computational approaches and results in protein structure analysis stemming from the availability of complete genomes. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：1 / 17

页数：17

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