Review of cognition and brain structure in schizophrenia: profiles, longitudinal course, and effects of treatment

被引：69

作者：

Flashman, LA

Green, MF

机构：

[1] Dartmouth Coll Sch Med, Dept Psychiat, Dartmouth Hitchcock Med Ctr, Lebanon, NH 03756 USA

[2] New Hampshire Hosp, Concord, NH 03301 USA

[3] Univ Calif Los Angeles, Inst Neuropsychiat, Los Angeles, CA 90024 USA

[4] Vet Adm Greater Los Angeles Healthcare Syst, Los Angeles, CA USA

来源：

PSYCHIATRIC CLINICS OF NORTH AMERICA | 2004年 / 27卷 / 01期

关键词：

D O I：

10.1016/S0193-953X(03)00105-9

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Schizophrenia is a serious, chronic mental illness that presents with neurocognitive and neuroanatomic abnormalities. This article briefly reviews the literature on the neurocognitive and neuroanatomic profiles of individuals with schizophrenia and addresses the issue of whether these performance deficits and structural abnormalities are stable across the course of the illness. Finally, the article discusses the effects of psychopharmacology on the neurocognitive deficits seen in patients with schizophrenia, examining the effects of conventional and atypical antipsychotics.

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页码：1 / +

页数：28

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