Trimethylsilyl chloride-accelerated reduction and pinacol coupling of carbonyl compounds by means of samarium diiodide

被引：18

作者：

Honda, T

Katoh, M

机构：

[1] Institute of Medicinal Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 04期

关键词：

D O I：

10.1039/a607774i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The combination of samarium diiodide (SmI2) and trimethylsilyl chloride (Me(3)SiCl) in THF-HMPA is found to accelerate the reduction of sterically hindered and enolisable ketones, and also to accelerate pinacolisation of the carbonyl compounds depending on the reaction conditions.

引用

收藏

页码：369 / 370

页数：2

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