Menopause, oestrogens and arthritis

被引:169
作者
Wluka, A [1 ]
Cicuttini, FM
Spector, TD
机构
[1] Monash Univ, Alfred Hosp, Dept Epidemiol & Prevent Med, Prahran, Vic 3181, Australia
[2] St Thomas Hosp, Twin Res & Genet Epidemiol Unit, London SE1 7EH, England
基金
英国医学研究理事会;
关键词
menopause; arthritis; disease;
D O I
10.1016/S0378-5122(00)00118-3
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 [法学]; 0303 [社会学]; 100203 [老年医学];
摘要
The menopause coincides with the appearance of many of the common arthritic conditions and with the lessening of severity of others such as SLE. The hormonal changes that occur may modulate these diseases. Thus, hormonal manipulation may have either beneficial or detrimental effects on the incidence and activity of a number of common joint diseases. We review the evidence regarding the effect of the menopause and oestrogen replacement therapy on the pathogenesis, incidence and prevalence and disease activity of osteoarthritis, rheumatoid arthritis, systemic lupus erythematosus and carpal tunnel syndrome. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:183 / 199
页数:17
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