Efficient synthesis of 7-, 8- and 9-membered cyclic allyltitanium compounds and their stereoselective addition reaction with aldehydes and imines

被引：24

作者：

Hikichi, S ^{[1
]}

Gao, Y ^{[1
]}

Sato, F ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT BIOMOL ENGN,MIDORI KU,YOKOHAMA,KANAGAWA 226,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 16期

关键词：

D O I：

10.1016/S0040-4039(97)00484-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 7-, 8- and 9-membered cyclic allylic compounds 2 with (eta(2)-propene)Ti(O-i-Pr)(2) (1) via an oxidative addition pathway provides she corresponding allylic titanium compounds, which, in turn, react with aldehydes and imines stereoselectively, thus providing an efficient and stereoselective method for synthesizing cycloalkenes having a side chain at the allylic position. (C) 1997 Elsevier Science Ltd.

引用

页码：2867 / 2870

页数：4

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