Comparison of GnRH antagonist protocol with or without oral contraceptive pill pretreatment and GnRH agonist low-dose long protocol in low responders undergoing IVF/intracytoplasmic sperm injection

被引：45

作者：

Kim, Chung-Hoon ^{[1
]}

Jeon, Gyun-Ho

Cheon, Yong-Pil ^{[2
]}

Jeon, Ilkyung

Kim, Sung-Hoon

Chae, Hee-Dong

Kang, Byung-Moon

机构：

[1] Univ Ulsan, Dept Obstet & Gynecol, Coll Med, Div Reprod Endocrinol & Infertil,Asan Med Ctr, Seoul, South Korea

[2] Sungshin Womens Univ, Coll Nat Sci, Dept Biol, Seoul, South Korea

来源：

FERTILITY AND STERILITY | 2009年 / 92卷 / 05期

关键词：

Oral contraceptive pill; GnRH antagonist protocol; GnRH agonist low-dose long protocol; low repsonders; OVARIAN STIMULATION; IVF; METAANALYSIS; RISK;

D O I：

10.1016/j.fertnstert.2009.05.013

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

This prospective randomized study was performed to compare the efficacy of GnRH antagonist multiple-dose protocol (MDP) with or without oral contraceptive pill (OCP) pretreatment and GnRH agonist low-dose long protocol (LP) in 82 patients undergoing IVF/intracytoplasmic sperm injection (ICSI). GnRH antagonist MDP with OCP pretreatment was at least as effective as GnRH agonist low-dose LP in low responders, and can benefit the low responders by reducing the amount of FSH and the number of days of stimulation required for follicular maturation. (Fertil Steril (R) 2009;92:1758-60. (C) 2009 by American Society for Reproductive Medicine.)

引用

页码：1758 / 1760

页数：3

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