Dictyostelium development: Lower STATs

被引:13
作者
Kay, RR
机构
关键词
D O I
10.1016/S0960-9822(06)00366-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The discovery of a STAT protein in Dictyostelium indicates that this organism uses phosphotyrosine-SH2-domain signalling during development. Such signalling is lacking in yeast and its appearance may therefore be an early step in the evolution of multicellularity. (C) Current Biology Ltd ISSN 0960-9822.
引用
收藏
页码:R723 / R725
页数:3
相关论文
共 11 条
[1]  
BALDAUF SL, 1997, IN PRESS P NATL ACAD
[2]   JAK-STAT PATHWAYS AND TRANSCRIPTIONAL ACTIVATION IN RESPONSE TO IFNS AND OTHER EXTRACELLULAR SIGNALING PROTEINS [J].
DARNELL, JE ;
KERR, IM ;
STARK, GR .
SCIENCE, 1994, 264 (5164) :1415-1421
[3]   Ligand binding was acquired during evolution of nuclear receptors [J].
Escriva, H ;
Safi, R ;
Hanni, C ;
Langlois, MC ;
SaumitouLaprade, P ;
Stehelin, D ;
Capron, A ;
Pierce, R ;
Laudet, V .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (13) :6803-6808
[4]  
Gamper M, 1996, MOL CELL BIOL, V16, P2431
[5]  
HARWOOD AJ, 1993, DEVELOPMENT, V118, P1041
[6]   The protein kinases of budding yeast: Six score and more [J].
Hunter, T ;
Plowman, GD .
TRENDS IN BIOCHEMICAL SCIENCES, 1997, 22 (01) :18-22
[7]   A SPECIFIC DIF BINDING-PROTEIN IN DICTYOSTELIUM [J].
INSALL, R ;
KAY, RR .
EMBO JOURNAL, 1990, 9 (10) :3323-3328
[8]   Evidence that a combined activator-repressor protein regulates Dictyostelium stalk cell differentiation [J].
Kawata, T ;
Early, A ;
Williams, J .
EMBO JOURNAL, 1996, 15 (12) :3085-3092
[9]   SH2 signaling in a lower eukaryote: A STAT protein that regulates stalk cell differentiation in Dictyostelium [J].
Kawata, T ;
Shevchenko, A ;
Fukuzawa, M ;
Jermyn, KA ;
Totty, NF ;
Zhukovskaya, NV ;
Sterling, AE ;
Mann, M ;
Williams, JG .
CELL, 1997, 89 (06) :909-916
[10]   CHEMICAL-STRUCTURE OF THE MORPHOGEN DIFFERENTIATION INDUCING FACTOR FROM DICTYOSTELIUM-DISCOIDEUM [J].
MORRIS, HR ;
TAYLOR, GW ;
MASENTO, MS ;
JERMYN, KA ;
KAY, RR .
NATURE, 1987, 328 (6133) :811-814