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Impact of CYP2C19 polymorphisms on the clinical action of proton pump inhibitors (PPIs)
被引:20
作者
:
Klotz, Ulrich
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
Univ Tubingen, Tubingen, Germany
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
Klotz, Ulrich
[
1
,
2
]
机构
:
[1]
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
[2]
Univ Tubingen, Tubingen, Germany
来源
:
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
|
2009年
/ 65卷
/ 01期
关键词
:
CLOPIDOGREL;
ESOMEPRAZOLE;
RABEPRAZOLE;
METABOLISM;
GENOTYPE;
D O I
:
10.1007/s00228-008-0571-x
中图分类号
:
R9 [药学];
学科分类号
:
1007 ;
摘要
:
引用
收藏
页码:1 / 2
页数:2
相关论文
共 14 条
[1]
Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin
Gilard, Martine
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Cardiol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Gilard, Martine
Arnaud, Bertrand
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, INSERM 0502, Dept Hematol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Arnaud, Bertrand
Cornily, Jean-Christophe
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Cardiol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Cornily, Jean-Christophe
Le Gal, Gregoire
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Internal Med & Chest Dis, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Le Gal, Gregoire
Lacut, Karine
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Ctr Clin Invest, EA3878, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Lacut, Karine
Le Calvez, Genevive
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, INSERM 0502, Dept Hematol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Le Calvez, Genevive
Mansourati, Jacques
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Cardiol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Mansourati, Jacques
Mottier, Dominique
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Internal Med & Chest Dis, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Mottier, Dominique
Abgrall, Jean-Francois
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, INSERM 0502, Dept Hematol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Abgrall, Jean-Francois
Boschat, Jacques
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Cardiol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Boschat, Jacques
[J].
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,
2008,
51
(03)
: 256
-
260
[2]
A possible new candidate influencing the antiplatelet effect of clopidogrel
Gurbel, Paul A.
论文数:
0
引用数:
0
h-index:
0
机构:
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Gurbel, Paul A.
Lau, Wei C.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Anesthesiol, Hlth Syst, Ann Arbor, MI 48109 USA
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Lau, Wei C.
Tantry, Udaya S.
论文数:
0
引用数:
0
h-index:
0
机构:
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Tantry, Udaya S.
[J].
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,
2008,
51
(03)
: 261
-
263
[3]
Review article: relationship between the metabolism and efficacy of proton pump inhibitors - focus on rabeprazole
Horn, J
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Washington, Dept Pharm, Seattle, WA 98195 USA
Univ Washington, Dept Pharm, Seattle, WA 98195 USA
Horn, J
[J].
ALIMENTARY PHARMACOLOGY & THERAPEUTICS,
2004,
20
: 11
-
19
[4]
Cytochrorne P4502C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
Hulot, Jean-Sebastien
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Hulot, Jean-Sebastien
Bura, Alessandra
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Bura, Alessandra
Villard, Eric
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Villard, Eric
Azizi, Michel
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Azizi, Michel
Remones, Veronique
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Remones, Veronique
Goyenvalle, Catherine
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Goyenvalle, Catherine
Aiach, Martine
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Aiach, Martine
Lechat, Philippe
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Lechat, Philippe
Gaussem, Pascale
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Gaussem, Pascale
[J].
BLOOD,
2006,
108
(07)
: 2244
-
2247
[5]
The effect of the area under the plasma concentration vs time curve and the maximum plasma concentration of esomeprazole on intragastric pH
Junghard, O
论文数:
0
引用数:
0
h-index:
0
机构:
AstraZeneca R&D, S-43183 Molndal, Sweden
AstraZeneca R&D, S-43183 Molndal, Sweden
Junghard, O
Hassan-Alin, M
论文数:
0
引用数:
0
h-index:
0
机构:
AstraZeneca R&D, S-43183 Molndal, Sweden
AstraZeneca R&D, S-43183 Molndal, Sweden
Hassan-Alin, M
Hasselgren, G
论文数:
0
引用数:
0
h-index:
0
机构:
AstraZeneca R&D, S-43183 Molndal, Sweden
AstraZeneca R&D, S-43183 Molndal, Sweden
Hasselgren, G
[J].
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY,
2002,
58
(07)
: 453
-
458
[6]
Pharmacogenetics-based therapeutic recommendations -: ready for clinical practice?
Kirchheiner, J
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cologne, Dept Pharmacol, D-50931 Cologne, Germany
Kirchheiner, J
Fuhr, U
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cologne, Dept Pharmacol, D-50931 Cologne, Germany
Fuhr, U
Brockmöller, J
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cologne, Dept Pharmacol, D-50931 Cologne, Germany
Brockmöller, J
[J].
NATURE REVIEWS DRUG DISCOVERY,
2005,
4
(08)
: 639
-
647
[7]
CYPC19 polymorphism and proton pump inhibitors
Klotz, U
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
Klotz, U
Schwab, M
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
Schwab, M
Treiber, G
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
Treiber, G
[J].
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY,
2004,
95
(01)
: 2
-
8
[8]
Klotz U, 2006, INT J CLIN PHARM TH, V44, P297
[9]
LOU HY, 2008, EUR J CLIN IN PRESS
[10]
Esomeprazole-induced healing of gastroesophageal reflux disease is unrelated to the genotype of CYP2C19:: Evidence from clinical and pharmacokinetic data
Schwab, M
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Schwab, M
Klotz, U
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Klotz, U
Hofmann, U
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Hofmann, U
Schaeffeler, E
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Schaeffeler, E
Leodolter, A
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Leodolter, A
Malfertheiner, P
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Malfertheiner, P
Treiber, G
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Treiber, G
[J].
CLINICAL PHARMACOLOGY & THERAPEUTICS,
2005,
78
(06)
: 627
-
634
←
1
2
→
共 14 条
[1]
Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin
Gilard, Martine
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Cardiol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Gilard, Martine
Arnaud, Bertrand
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, INSERM 0502, Dept Hematol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Arnaud, Bertrand
Cornily, Jean-Christophe
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Cardiol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Cornily, Jean-Christophe
Le Gal, Gregoire
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Internal Med & Chest Dis, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Le Gal, Gregoire
Lacut, Karine
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Ctr Clin Invest, EA3878, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Lacut, Karine
Le Calvez, Genevive
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, INSERM 0502, Dept Hematol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Le Calvez, Genevive
Mansourati, Jacques
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Cardiol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Mansourati, Jacques
Mottier, Dominique
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Internal Med & Chest Dis, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Mottier, Dominique
Abgrall, Jean-Francois
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, INSERM 0502, Dept Hematol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Abgrall, Jean-Francois
Boschat, Jacques
论文数:
0
引用数:
0
h-index:
0
机构:
Brest Univ Hosp, Dept Cardiol, Brest, France
Brest Univ Hosp, Dept Cardiol, Brest, France
Boschat, Jacques
[J].
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,
2008,
51
(03)
: 256
-
260
[2]
A possible new candidate influencing the antiplatelet effect of clopidogrel
Gurbel, Paul A.
论文数:
0
引用数:
0
h-index:
0
机构:
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Gurbel, Paul A.
Lau, Wei C.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Anesthesiol, Hlth Syst, Ann Arbor, MI 48109 USA
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Lau, Wei C.
Tantry, Udaya S.
论文数:
0
引用数:
0
h-index:
0
机构:
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Sinai Hosp, Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
Tantry, Udaya S.
[J].
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,
2008,
51
(03)
: 261
-
263
[3]
Review article: relationship between the metabolism and efficacy of proton pump inhibitors - focus on rabeprazole
Horn, J
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Washington, Dept Pharm, Seattle, WA 98195 USA
Univ Washington, Dept Pharm, Seattle, WA 98195 USA
Horn, J
[J].
ALIMENTARY PHARMACOLOGY & THERAPEUTICS,
2004,
20
: 11
-
19
[4]
Cytochrorne P4502C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
Hulot, Jean-Sebastien
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Hulot, Jean-Sebastien
Bura, Alessandra
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Bura, Alessandra
Villard, Eric
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Villard, Eric
Azizi, Michel
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Azizi, Michel
Remones, Veronique
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Remones, Veronique
Goyenvalle, Catherine
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Goyenvalle, Catherine
Aiach, Martine
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Aiach, Martine
Lechat, Philippe
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Lechat, Philippe
Gaussem, Pascale
论文数:
0
引用数:
0
h-index:
0
机构:
Hop Europeen Georges Pompidou, Serv Hematol Biol A, INSERM, U765, F-75908 Paris 15, France
Gaussem, Pascale
[J].
BLOOD,
2006,
108
(07)
: 2244
-
2247
[5]
The effect of the area under the plasma concentration vs time curve and the maximum plasma concentration of esomeprazole on intragastric pH
Junghard, O
论文数:
0
引用数:
0
h-index:
0
机构:
AstraZeneca R&D, S-43183 Molndal, Sweden
AstraZeneca R&D, S-43183 Molndal, Sweden
Junghard, O
Hassan-Alin, M
论文数:
0
引用数:
0
h-index:
0
机构:
AstraZeneca R&D, S-43183 Molndal, Sweden
AstraZeneca R&D, S-43183 Molndal, Sweden
Hassan-Alin, M
Hasselgren, G
论文数:
0
引用数:
0
h-index:
0
机构:
AstraZeneca R&D, S-43183 Molndal, Sweden
AstraZeneca R&D, S-43183 Molndal, Sweden
Hasselgren, G
[J].
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY,
2002,
58
(07)
: 453
-
458
[6]
Pharmacogenetics-based therapeutic recommendations -: ready for clinical practice?
Kirchheiner, J
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cologne, Dept Pharmacol, D-50931 Cologne, Germany
Kirchheiner, J
Fuhr, U
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cologne, Dept Pharmacol, D-50931 Cologne, Germany
Fuhr, U
Brockmöller, J
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cologne, Dept Pharmacol, D-50931 Cologne, Germany
Brockmöller, J
[J].
NATURE REVIEWS DRUG DISCOVERY,
2005,
4
(08)
: 639
-
647
[7]
CYPC19 polymorphism and proton pump inhibitors
Klotz, U
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
Klotz, U
Schwab, M
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
Schwab, M
Treiber, G
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
Treiber, G
[J].
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY,
2004,
95
(01)
: 2
-
8
[8]
Klotz U, 2006, INT J CLIN PHARM TH, V44, P297
[9]
LOU HY, 2008, EUR J CLIN IN PRESS
[10]
Esomeprazole-induced healing of gastroesophageal reflux disease is unrelated to the genotype of CYP2C19:: Evidence from clinical and pharmacokinetic data
Schwab, M
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Schwab, M
Klotz, U
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Klotz, U
Hofmann, U
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Hofmann, U
Schaeffeler, E
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Schaeffeler, E
Leodolter, A
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Leodolter, A
Malfertheiner, P
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Malfertheiner, P
Treiber, G
论文数:
0
引用数:
0
h-index:
0
机构:
Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
Treiber, G
[J].
CLINICAL PHARMACOLOGY & THERAPEUTICS,
2005,
78
(06)
: 627
-
634
←
1
2
→