Picroliv protects against alcohol-induced chronic hepatotoxicity in rats

被引：34

作者：

Rastogi, R

Saksena, S

Garg, NK

Kapoor, NK

Agarwal, DP

Dhawan, BN

机构：

[1] CENT DRUG RES INST,ICMR,CTR ADV RES TRADIT REMEDIES,LUCKNOW 226001,UTTAR PRADESH,INDIA

[2] CENT DRUG RES INST,DIV BIOCHEM,LUCKNOW 226001,UTTAR PRADESH,INDIA

[3] UNIV HAMBURG,INST HUMAN GENET,D-2000 HAMBURG,GERMANY

来源：

PLANTA MEDICA | 1996年 / 62卷 / 03期

关键词：

D O I：

10.1055/s-2006-957882

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Daily administration of ethyl alcohol (3.76 g/kg, p.o.) for 45 days resulted in significant changes in several biochemical parameters of the liver and serum of albino rats. After exposure to alcohol for 30 days when Picroliv (12 mg/kg, p.o.), an iridoid glycoside fraction of Picrorhiza kurroa, was administered for 15 days along with alcohol, the degree of change in most of the parameters was reduced.

引用

页码：283 / 285

页数：3

共 11 条

[1]

AGARWAL DP, 1990, ALCOHOL METABOLISM A, P126

[2]

ANSARI RA, 1988, INDIAN J MED RES, V87, P401

[3]

CHANDER R, 1988, BIOCH LIFE SCI ADV, V7, P25

[4]

PICROLIV AND ITS COMPONENTS KUTKOSIDE AND PICROSIDE I PROTECT LIVER AGAINST GALACTOSAMINE-INDUCED DAMAGE IN RATS [J].