Functional connectivity in auditory cortex using chronic, multichannel unit recordings

被引：7

作者：

Clement, RS ^{[1
]}

Witte, RS ^{[1
]}

Rousche, PJ ^{[1
]}

Kipke, DR ^{[1
]}

机构：

[1] Arizona State Univ, Bioengn Program, Tempe, AZ 85287 USA

来源：

NEUROCOMPUTING | 1999年 / 26-7卷

关键词：

auditory cortex; correlation; plasticity; connectivity;

D O I：

10.1016/S0925-2312(99)00023-5

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

Chronic, multichannel recordings provide a method for reliable detection and determination of long-term dynamic functional connectivity. Using chronically implanted multichannel electrode arrays, we simultaneously recorded 30-70 units in guinea pig auditory cortex in daily recording sessions for implant durations of six months. We examined stimulus response properties and correlation strengths in neuron pairs in four animals. Preliminary results from these 'snapshots' of functional connectivity suggest sparse functional connections among widely distributed neurons. Some of these functional connections were found to persist for several days. These results provide a framework upon which further investigations of functional dynamic connectivity can be developed. (C) 1999 Published by Elsevier Science B.V. All rights reserved.

引用

页码：347 / 354

页数：8

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