The role of protease inhibition with emphasis on the effects of inflammation and vascular immune phenomena

被引：15

作者：

Bilfinger, TV ^{[1
]}

Stefano, GB ^{[1
]}

机构：

[1] SUNY Stony Brook, Hlth Sci Ctr, Dept Surg, Cardiothorac Div, Stony Brook, NY 11794 USA

来源：

CURRENT PHARMACEUTICAL DESIGN | 2002年 / 8卷 / 07期

关键词：

D O I：

10.2174/1381612023395763

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review discusses the role of protease inhibition with emphasis on the effects of inflammation and vascular immune phenomena in non-immunocompromised hosts. A vast body of knowledge elucidating the role of protease inhibition and hemostasis has accumulated in recent years. The two subjects are intimately linked, but the focus of this review is limited to the anti-inflammatory effects of protease inhibitors. In light of the particular expertise of the present authors, this review will focus on human studies and often cite work related to open-heart surgery, since in recent years this is the area in which a large effort has been concentrated worldwide.

引用

页码：505 / 509

页数：5

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