A clinical review of PDT for cutaneous malignancies

被引:44
作者
Allison, Ron R. [1 ]
Sibata, Claudio H. [1 ]
Downie, Gordon H. [1 ]
Cuenca, Rosa E. [1 ]
机构
[1] Brody Sch Med ECU, Dept Radiat Oncol, Leo Jenkins Canc Inst, PDT Ctr, Greenville, NC 27834 USA
关键词
PDT; Cutaneous malignancy; Topical photosensitizers; Intravenous photosensitizers; Skin cancer;
D O I
10.1016/j.pdpdt.2006.05.002
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
More critical than for most other anatomy, intervention to cutaneous malignancy must not only be therapeutically successful but also achieve excellent cosmetic and functional outcome. As it can achieve those ends, PDT has moved to the forefront in the management of skin cancer. A number of well designed clinical trials and large patient series have reported outstanding outcomes for many histologies. This paper will review the rationale and outcomes of cutaneous PDT to malignancy using both topical and systemic photosensitizers. The benefits and drawbacks of cutaneous PDT are also examined. (C) 2006 Published by Elsevier B.V.
引用
收藏
页码:214 / 226
页数:13
相关论文
共 115 条
  • [1] Targeting of the vascular system of solid tumours by photodynamic therapy (PDT)
    Abels, C
    [J]. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 2004, 3 (08) : 765 - 771
  • [2] Laser-mediated photodynamic therapy
    Alexiades-Armenakas, M
    [J]. CLINICS IN DERMATOLOGY, 2006, 24 (01) : 16 - 25
  • [3] Alexiades-Armenakas Macrene, 2005, J Drugs Dermatol, V4, P514
  • [4] Alexiades-Armenakas Macrene R, 2004, J Drugs Dermatol, V3, P548
  • [5] Allison R, 2001, CANCER, V91, P1, DOI 10.1002/1097-0142(20010101)91:1<1::AID-CNCR1>3.0.CO
  • [6] 2-P
  • [7] Clinical PD/PDT in North America: An historical review
    Allison, R. R.
    Mota, H. C.
    Sibata, C. H.
    [J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2004, 1 (04) : 263 - 277
  • [8] Photodynamic therapy for chest wall recurrence from breast cancer
    Allison, R. R.
    Sibata, C.
    Mang, T. S.
    Bagnato, V. S.
    Downie, G. H.
    Hu, X. H.
    Cuenca, R.
    [J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2004, 1 (02) : 157 - 171
  • [9] Photosensitizers in clinical PDT
    Allison, Ron R.
    Downie, Gordon H.
    Cuenca, Rosa
    Hu, Xin-Hua
    Childs, Carter J. H.
    Sibata, Claudio H.
    [J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2004, 1 (01) : 27 - 42
  • [10] Photodynamic therapy for the treatment of nonmelanomatous cutaneous malignancies
    Allison, RR
    Mang, TS
    Wilson, BD
    [J]. SEMINARS IN CUTANEOUS MEDICINE AND SURGERY, 1998, 17 (02) : 153 - 163