Evaluation of the stability of intracortical microelectrode arrays

被引:65
作者
Liu, XD [1 ]
McCreery, DB [1 ]
Bullara, LA [1 ]
Agnew, WF [1 ]
机构
[1] Huntington Med Res Inst, Neural Engn Program, Pasadena, CA 91105 USA
关键词
brain-machine interface; cat cortex; chronic microelectrode implants; neuroprosthesis; stabilit;
D O I
10.1109/TNSRE.2006.870495
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In order to use recorded neural activities from the brain as control signals for neuroprosthesis devices, it is important to maintain a stable interface between chronically implanted microelectrodes and neural tissue. Our previous paper introduced a method to quantify the stability of the recording microelectrodes. In this paper, the method is refined 1) by incorporating stereotypical behavioral patterns into the spike sorting program and 2) by using a classifier based on Bayes theorem for assigning the recorded action potentials to the underlying neural generators. An improved method for calculating stability index is proposed. The results for the stability of microelectrode arrays that differ in structure are presented.
引用
收藏
页码:91 / 100
页数:10
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