Methazolamide for essential voice tremor

被引：29

作者：

Busenbark, K ^{[1
]}

Ramig, L ^{[1
]}

Dromey, C ^{[1
]}

Koller, WC ^{[1
]}

机构：

[1] UNIV COLORADO, DEPT COMMUN DISORDERS & SPEECH SCI, BOULDER, CO 80309 USA

来源：

NEUROLOGY | 1996年 / 47卷 / 05期

关键词：

D O I：

10.1212/WNL.47.5.1331

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied the safety and efficacy of methazolamide (average dose 168 mg/day) in a placebo-controlled blinded investigation in nine patients with essential voice tremor. There were no significant differences for physician or patient clinical rating scores. Digital audio tape recordings showed no difference for amplitude modulation, but frequency modulation was significantly altered by methazolamide. Side effects were common with the drug. We conclude that methazolamide has limited usefulness in the treatment of essential voice tremor.

引用

页码：1331 / 1332

页数：2

共 10 条

[1] ORGANIC VOICE TREMOR - A TREMOR OF PHONATION [J].

BROWN, JR ;

SIMONSON, J .

NEUROLOGY, 1963, 13 (06) :520-&

[2] DOUBLE-BLIND CONTROLLED-STUDY OF METHAZOLAMIDE IN THE TREATMENT OF ESSENTIAL TREMOR [J].

BUSENBARK, K ;

PAHWA, R ;

HUBBLE, J ;

HOPFENSPERGER, K ;

KOLLER, W .

NEUROLOGY, 1993, 43 (05) :1045-1047

[3] IS ESSENTIAL TREMOR BENIGN [J].

BUSENBARK, KL ;

NASH, J ;

NASH, S ;

HUBBLE, JP ;

KOLLER, WC .

NEUROLOGY, 1991, 41 (12) :1982-1983

[4] ESSENTIAL VOICE TREMOR - TREATMENT WITH PROPRANOLOL [J].

KOLLER, W ;

GRANER, D ;

MLCOCH, A .

NEUROLOGY, 1985, 35 (01) :106-108

[5] THE RELATIONSHIP OF ESSENTIAL TREMOR TO OTHER MOVEMENT-DISORDERS - REPORT ON 678 PATIENTS [J].

KOLLER, WC ;

BUSENBARK, K ;

MINER, K ;

ADAIR, JC ;

AIGNER, BR ;

ALBIN, RI ;

ALEXANDER, DN ;

ANTO, CM ;

BENDER, SE ;

BERG, MJ ;

BERGIA, BM ;

BLALOCK, E ;

BURNS, RS ;

COUCH, JR ;

CRISOSTOMO, EA ;

DAVIS, LS ;

DAVIS, TL ;

DIETRICH, DW ;

DIMITSOPULOS, TM ;

DOORENBOS, D ;

ELLIS, JR ;

ERTAG, WD ;

FACTOR, SA ;

FEIGIN, AS ;

FREY, KA ;

GADDIS, KA ;

GIBSON, GL ;

GOLDEN, RE ;

GORDON, MF ;

GREENAMYRE, JT ;

GRIFFITH, PA ;

GROTTA, JC ;

HAUSER, RA ;

HEIDEBRINK, JL ;

HIGGINS, DC ;

HILL, SA ;

HILL, TA ;

HUBBLE, JP ;

HUTTON, JT ;

JOHNSTON, W ;

KIEBURTZ, KD ;

KURLAN, RM ;

LABUNETZ, WH ;

LIEBERMAN, AN ;

MAJUMDAR, L ;

MARAGOS, WF ;

MCCLOSKEY, T ;

MCPHERSON, SL ;

MILLER, BR ;

NINO, HE .

ANNALS OF NEUROLOGY, 1994, 35 (06) :717-723

[6]

Koller WC, 1994, NEURODEGENER DIS, P717

[7]

LARSSON TAGE, 1960, ACTA PSYCHIAT ET NEUROL SCAND SUPPL, V36, P1

[8]

MASSEY EW, 1985, S MED J, V7, P316

[9] TREATMENT OF ESSENTIAL TREMOR WITH METHAZOLAMIDE [J].

MUENTER, MD ;

DAUBE, JR ;

CAVINESS, JN ;

MILLER, PM .

MAYO CLINIC PROCEEDINGS, 1991, 66 (10) :991-997

[10] VOCAL TREMOR ANALYSIS WITH THE VOCAL DEMODULATOR [J].

WINHOLTZ, WS ;

RAMIG, LO .

JOURNAL OF SPEECH AND HEARING RESEARCH, 1992, 35 (03) :562-573

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