The "common cause hypothesis" of cognitive aging: Evidence for not only a common factor but also specific associations of with vision and grip strength in a cross-sectional analysis

被引:177
作者
Christensen, H
Mackinnon, AJ
Korten, A
Jorm, AF
机构
[1] Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT 0200, Australia
[2] Monash Univ, Mental Hlth Res Inst, Melbourne, Vic 3004, Australia
[3] Monash Univ, Dept Psychol Med, Melbourne, Vic 3004, Australia
关键词
D O I
10.1037//0882-7974.16.4.588
中图分类号
R4 [临床医学]; R592 [老年病学];
学科分类号
1002 ; 100203 ; 100602 ;
摘要
A prominent hypothesis in cognitive aging is the existence of a common factor that is responsible for age-related deterioration in cognitive and noncognitive processes. A multiple indicators, multiple causes model was used to examine the nature of this common factor and its relationship to ape, gender, and the apolipoprotein E (APOE) genotype, The common factor was modeled by using 10 indicator variables with 374 participants aged between 77.4 and 98.7 years. A latent factor was identified, with all indicators except blood pressure loading significantly. This factor could be established in 2 age strata within the sample. After controlling for the effects of gender, APOE, and level of education, direct effects of age were seen on visual functioning and grip strength. APOE was significantly associated with memory but not with the common factor. The findings suggest that a number of specific processes may operate concurrently with any common cause factor.
引用
收藏
页码:588 / 599
页数:12
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