Intestinal microsporidiosis due to Enterocytozoon bieneusi in elderly human immunodeficiency virus-negative patients from Vigo, Spain

被引：87

作者：

Lores, B

López-Miragaya, I

Arias, C

Fenoy, S

Torres, J

del Aguila, C

机构：

[1] Univ Vigo, Parasitol Lab, Vigo, Spain

[2] Hosp Meixoeiro, Microbiol Lab, Vigo, Spain

[3] Univ San Pablo, CEU, Secc Parasitol, Madrid, Spain

来源：

CLINICAL INFECTIOUS DISEASES | 2002年 / 34卷 / 07期

关键词：

D O I：

10.1086/339205

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report what is, to our knowledge, the first study in which microsporidial infection was detected in elderly human immunodeficiency virus (HIV)-negative patients. Of the 60 elderly patients studied, 47 had diarrhea. Intestinal microsporidiosis due to Enterocytozoon bieneusi was diagnosed in 8 patients (17.02%) by use of Weber's chromotrope-based stain and polymerase chain reaction with species-specific primers. The mean age of these 8 patients was 75 years; 7 had chronic diarrhea and 1 had nonchronic diarrhea. Six of the patients with chronic diarrhea had no other pathogens isolated. In our opinion, elderly patients, because of their special immunological characteristics, should be considered a group at risk for the acquisition of intestinal microsporidiosis.

引用

页码：918 / 921

页数：4

共 22 条

[1]

Ben-Yehuda A, 1992, Clin Geriatr Med, V8, P701

[2] Modification of the clinical course of intestinal microsporidiosis in acquired immunodeficiency syndrome patients by immune status and anti-human immunodeficiency virus therapy [J].

Conteas, CN ;

Berlin, OGW ;

Speck, CE ;

Pandhumas, SS ;

Lariviere, MJ ;

Fu, C .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1998, 58 (05) :555-558

[3] Fast and reliable extraction of protozoan parasite DNA from fecal specimens [J].

da Silva, AJ ;

Bornay-Llinares, FJ ;

Moura, INS ;

Slemenda, SB ;

Tuttle, JL ;

Pieniazek, NJ .

MOLECULAR DIAGNOSIS, 1999, 4 (01) :57-64

[4] Sensitive PCR diagnosis of infections by Enterocytozoon bieneusi (Microsporidia) using primers based on the region coding for small-subunit rRNA [J].

DaSilva, AJ ;

Schwartz, DA ;

Visvesvara, GS ;

DeMoura, H ;

Slemenda, SB ;

Pieniazek, NJ .

JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (04) :986-987

[5] Detection of Septata intestinalis (Microsporidia) Cali et al. 1993 using polymerase chain reaction primers targeting the small subunit ribosomal RNA coding region [J].

DaSilva, AJ ;

Slemenda, SB ;

Visvesvara, GS ;

Schwartz, DA ;

Wilcox, CM ;

Wallace, S ;

Pieniazek, NJ .

MOLECULAR DIAGNOSIS, 1997, 2 (01) :47-52

[6]

Del Aguila C, 1999, J EUKARYOT MICROBIOL, V46, p8S

[7] Identification of Enterocytozoon bieneusi spores in respiratory samples from an AIDS patient with a 2-year history of intestinal microsporidiosis [J].

delAguila, C ;

LopezVelez, R ;

Fenoy, S ;

Turrientes, C ;

Cobo, J ;

Navajas, R ;

Visvesvara, GS ;

Croppo, GP ;

DaSilva, AJ ;

Pieniazek, NJ .

JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (07) :1862-1866

[8] Microsporidiosis in HIV-seronegative patients in Mali [J].

Desportes-Livage, I ;

Doumbo, O ;

Pichard, E ;

Hilmarsdottir, I ;

Traoré, HA ;

Maiga, II ;

El Fakhry, Y ;

Dolo, A .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1998, 92 (04) :423-424

[9] Prevalence of intestinal encephalitozoonosis in Mexico [J].

Enriquez, FJ ;

Taren, D ;

Cruz-López, A ;

Muramoto, M ;

Palting, JD ;

Cruz, P .

CLINICAL INFECTIOUS DISEASES, 1998, 26 (05) :1227-1229

[10]

Fournier S, 2000, FEMS IMMUNOL MED MIC, V29, P95, DOI 10.1111/j.1574-695X.2000.tb01510.x

← 1 2 3 →