Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass

被引：207

作者：

Weiner, OD ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2002年 / 14卷 / 02期

关键词：

D O I：

10.1016/S0955-0674(02)00310-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Phosphatidylinositol 3-kinase lipid products and the Rho GTPases play a central role in transmitting information from chemotactic receptors to the effectors of cell polarity, and recent advances in the field have allowed us to understand these roles more clearly. Emergent properties of positive and negative regulation of these molecules may account for the establishment of cell polarity during chemotaxis for a wide range of cells from Dictyostelium to fibroblasts to neutrophils.

引用

页码：196 / 202

页数：7

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