Vitamin D and pregnancy

被引：3

作者：

Benachi, Alexandra ^{[1
,2
]}

Cordier, Anne-Gael ^{[1
]}

Courbebaisse, Marie ^{[3
]}

Souberbielle, Jean-Claude ^{[4
]}

机构：

[1] Univ Paris 11, Hop Antoine Beclere, AP HP, Serv Gynecol Obstet & Med Reprod, F-92141 Clamart, France

[2] PremUP, F-75014 Paris, France

[3] Univ Paris 05, Hop Europeen Georges Pompidou, Croissance & Signalisat Cellulaire Equipe Homeost, INSERM,U845,Serv Physiol Explorat Fonct, F-75015 Paris, France

[4] Univ Paris 05, Hop Necker Enfants Malad, AP HP, Serv Physiol Explorat Fonct, F-75015 Paris, France

来源：

PRESSE MEDICALE | 2013年 / 42卷 / 10期

关键词：

D DEFICIENCY; D SUPPLEMENTATION; HIGH-RISK; PREECLAMPSIA; METABOLISM; OUTCOMES; CALCIUM;

D O I：

10.1016/j.lpm.2013.07.007

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Vitamin D insufficiency is characterized, since 2005, by 25(OH)D concentration less than 75 nmol/L (or 30 ng/mL). Vitamin D could interfere with many mechanisms involved in preeclampsia's pathogenesis including trophoblastic invasion and immunomodulation as well as blood pressure control and proteinuria. Occurrence of preeclampsia and gestational diabetes seems to be linked to vitamin D deficiency but recent data in the literature are contradictory. Vitamin D supplementation during pregnancy is controversial Some societies consider it unnecessary and others recommend up to 2000 Ul/d. There is no reported case of teratogenicity linked with vitamin D intake.

引用

页码：1377 / 1382

页数：6

共 38 条

[1]

ACOG American College of Obstetricians and Gynecologists, 2011, OBSTET GYNECOL, V118, P197, DOI DOI 10.1097/A0G.0B013E318227F06B

[2]

[Anonymous], 2004, COCHRANE DB SYST REV

[3]

First-trimester maternal vitamin D status and risk for gestational diabetes (GDM) a nested case-control study [J].