Organic reaction in water. Part 2: Michael addition in water without phase transfer agents

被引：28

作者：

da Silva, FM ^{[1
]}

Gomes, AK ^{[1
]}

Jones, J ^{[1
]}

机构：

[1] Univ Fed Rio de Janeiro, Dept Quim Organ, Inst Quim, BR-20910240 Rio De Janeiro, Brazil

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1999年 / 77卷 / 5-6期

关键词：

Michael addition; aqueous media; water; 2-cyclohexen-1-one; ketone;

D O I：

10.1139/cjc-77-5-6-624

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Michael additions of dicarbonyl compounds, nitroalkanes, and thiols to 2-cyclohexen-1-one can be accomplished in water without phase transfer agents. The reaction is extremely sensitive to the pH of the reaction media, and therefore, the methodology can be optimized with the control of this variable. The best pH depends on the used nucleophile.

引用

页码：624 / 627

页数：4

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