A mild and efficient one-pot synthesis of 1-hydroxymethylene-1,1-bisphosphonic acids. Preparation of new tripod ligands

被引：96

作者：

Lecouvey, M ^{[1
]}

Mallard, I ^{[1
]}

Burgada, R ^{[1
]}

Leroux, Y ^{[1
]}

机构：

[1] Univ Paris 13, UFR SMBH, CNRS, FRE 2313,Lab Chim Struct Biomol, F-93017 Bobigny, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(01)01844-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient one-pot procedure for synthesis of 1-hydroxymethyleiie-1,1-bisphosphonic acids by reaction of acyl chlorides and tris(trimethylsilyl)phosphite is described. This method was applied to the synthesis of new phosphonated chelating tripod ligands. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：8475 / 8478

页数：4

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