Topical Mitomycin C application for esophageal stricture: Safe, precise, and novel endoscopic technique

Purpose: The first line of management of benign esophageal stricture is endoscopic dilatation; however, multiple sessions are usually indicated especially in resistant cases. Topical Mitomycin C (MCC) application is a new adjuvant treatment in the management of esophageal stricture with promising results in different case series. Several techniques have been reported for application; nevertheless, the ideal technique has not been described yet. Material and Methods: In this series we have devised a new technique using both the flexible and the rigid endoscope and a specially designed Nelaton catheter. Results: This technique was applied in 38 sessions for 16 caustic esophageal strictures with technical success in all cases. No procedure-related complications were observed in this series. Conclusion: This novel technique is feasible and effective and can be considered as standard for topical MMC application on esophageal stricture. (c) 2013 Elsevier Inc. All rights reserved.