Recent Advances in Microwave-Based Dielectric Spectroscopy at the Cellular Level for Cancer Investigations

被引:163
作者
Grenier, Katia [1 ]
Dubuc, David [1 ]
Chen, Tong [1 ]
Artis, Francois [1 ]
Chretiennot, Thomas [1 ]
Poupot, Mary [2 ]
Fournie, Jean-Jacques [2 ]
机构
[1] Natl Sci Res Ctr LAAS CNRS, Lab Anal & Architecture Syst, F-31400 Toulouse, France
[2] Canc Res Ctr Toulouse, F-31000 Toulouse, France
关键词
Biology; cancer; cells; dielectric spectroscopy; microwave; IMPEDANCE CYTOMETRY; CELLS; PERMITTIVITY; WATER; SENSORS; TISSUES; RANGE; THZ;
D O I
10.1109/TMTT.2013.2255885
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Cancer remains a leading cause of death in the world. To overcome this problem, it is necessary to develop new analysis tools, in complementarity to existing ones, to enable the early diagnostic of the diseases, personalized treatment, and further fundamental cancer mechanisms understanding. In this context, microwave-based and millimeter-wave-based dielectric spectroscopy performed at the cellular and molecular levels is progressively emerging, as it permits the non-invasive and real-time probing of cells in their culture biological medium. The recent advances of this topic are given in this paper with a specific highlight of its various assets.
引用
收藏
页码:2023 / 2030
页数:8
相关论文
共 58 条
[1]  
[Anonymous], P 13 INT SOL SAT SEN
[2]  
[Anonymous], IEEE MTT S INT MICR
[3]  
[Anonymous], 5 INT MICR MED BIOL
[4]   MICROWAVE DIELECTRIC MEASUREMENTS OF ERYTHROCYTE SUSPENSIONS [J].
BAO, JZ ;
DAVIS, CC ;
SWICORD, ML .
BIOPHYSICAL JOURNAL, 1994, 66 (06) :2173-2180
[5]   Recent advances in electric analysis of cells in microfluidic systems [J].
Bao, Ning ;
Wang, Jun ;
Lu, Chang .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2008, 391 (03) :933-942
[6]   Microwave Debye relaxation analysis of dissolved proteins: Towards free-solution biosensing [J].
Basey-Fisher, T. H. ;
Hanham, S. M. ;
Andresen, H. ;
Maier, S. A. ;
Stevens, M. M. ;
Alford, N. M. ;
Klein, N. .
APPLIED PHYSICS LETTERS, 2011, 99 (23)
[7]   BioMEMS: state-of-the-art in detection, opportunities and prospects [J].
Bashir, R .
ADVANCED DRUG DELIVERY REVIEWS, 2004, 56 (11) :1565-1586
[8]   Broadband permittivity measurements of liquid and biological samples using microfluidic channels [J].
Booth, James C. ;
Mateu, J. ;
Janezic, Michael ;
Baker-Jarvis, James ;
Beall, James A. .
2006 IEEE MTT-S INTERNATIONAL MICROWAVE SYMPOSIUM DIGEST, VOLS 1-5, 2006, :1750-+
[9]   Quantitative Permittivity Measurements of Nanoliter Liquid Volumes in Microfluidic Channels to 40 GHz [J].
Booth, James C. ;
Orloff, Nathan D. ;
Mateu, Jordi ;
Janezic, Michael ;
Rinehart, Matthew ;
Beall, James A. .
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2010, 59 (12) :3279-3288
[10]   The dielectric relaxation of water between 0°C and 35°C [J].
Buchner, R ;
Barthel, J ;
Stauber, J .
CHEMICAL PHYSICS LETTERS, 1999, 306 (1-2) :57-63