Palladium-catalyzed C-H homocoupling of thiophenes: Facile construction of bithiophene structure

被引：283

作者：

Masui, K ^{[1
]}

Ikegami, H ^{[1
]}

Mori, A ^{[1
]}

机构：

[1] Tokyo Inst Technol, Chem Resources Lab, Yokohama, Kanagawa 2268503, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 16期

关键词：

D O I：

10.1021/ja031855p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Palladium-catalyzed C-H homocoupling of thiophene derivatives takes place in the presence of silver(I) fluoride or acetate. A variety of bithiophenes are obtained in good to excellent yields. In particular, the reaction of 2-bromothiophene proceeds at room temperature to afford 5,5′-dibromo-2,2′-bithiophene, where the bromine atom is completely intact in the palladium-catalyzed reaction. XRD analysis reveals that silver fluoride is reduced to silver(0) during the reaction. Copyright © 2003 American Chemical Society.

引用

页码：5074 / 5075

页数：2

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