Tandem ring opening ring closing metathesis of cyclic olefins

被引：232

作者：

Zuercher, WJ ^{[1
]}

Hashimoto, M ^{[1
]}

Grubbs, RH ^{[1
]}

机构：

[1] CALTECH,DIV CHEM & CHEM ENGN,ARNOLD & MABEL BECKMAN LABS CHEM SYNTHESIS,PASADENA,CA 91125

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 118卷 / 28期

关键词：

D O I：

10.1021/ja9606743

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ruthenium alkylidene 1 has been utilized in the tandem ring opening-ring closing metathesis of cyclic olefins, This reaction produces a bicyclic molecule from a cyclic olefin. Reactivity is dependent upon strain, and thus ring size, in the substrate molecules. Competing oligomerization is observed in substrates having low ring strain; this process is inhibited by increasing dilution of the reaction or by adding alkyl substitution to the acyclic olefins.

引用

页码：6634 / 6640

页数：7

共 31 条

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