Wnt signalling:: A moving picture emerges from van gogh

被引:16
作者
Heisenberg, CP
Tada, M
机构
[1] Max Planck Inst Mol Cell Biol & Genet, D-01307 Dresden, Germany
[2] UCL, Dept Anat & Dev Biol, London WC1E 6BT, England
关键词
D O I
10.1016/S0960-9822(02)00704-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent studies on vertebrate homologues of the van gogh/strabismus (vang/stbm) gene, a key player in planar cell polarity signalling in Drosophila, show that vang/stbm is involved in patterning and morphogenesis during vertebrate gastrulation where it modulates two distinct Wnt signals.
引用
收藏
页码:R126 / R128
页数:3
相关论文
共 20 条
[1]   Frizzled signaling and cell-cell interactions in planar polarity [J].
Adler, PN ;
Lee, H .
CURRENT OPINION IN CELL BIOLOGY, 2001, 13 (05) :635-640
[2]  
Axelrod JD, 2001, GENE DEV, V15, P1182
[3]   Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways [J].
Axelrod, JD ;
Miller, JR ;
Shulman, JM ;
Moon, RT ;
Perrimon, N .
GENES & DEVELOPMENT, 1998, 12 (16) :2610-2622
[4]   The ankyrin repeat protein diego mediates Frizzled-dependent planar polarization [J].
Feiguin, F ;
Hannus, M ;
Mlodzik, M ;
Eaton, S .
DEVELOPMENTAL CELL, 2001, 1 (01) :93-101
[5]   Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation [J].
Heisenberg, CP ;
Tada, M ;
Rauch, GJ ;
Saúde, L ;
Concha, ML ;
Geisler, R ;
Stemple, DL ;
Smith, JC ;
Wilson, SW .
NATURE, 2000, 405 (6782) :76-81
[6]   Mechanisms of convergence and extension by cell intercalation [J].
Keller, R ;
Davidson, L ;
Edlund, A ;
Elul, T ;
Ezin, M ;
Shook, D ;
Skoglund, P .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2000, 355 (1399) :897-922
[7]   Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail [J].
Kibar, Z ;
Vogan, KJ ;
Groulx, N ;
Justice, MJ ;
Underhill, DA ;
Gros, P .
NATURE GENETICS, 2001, 28 (03) :251-255
[8]  
Kiecker C, 2001, DEVELOPMENT, V128, P4189
[9]  
KIMMEL CB, 1990, DEVELOPMENT, V108, P581
[10]   Planar polarity in the Drosophila eye:: a multifaceted view of signaling specificity and cross-talk [J].
Mlodzik, M .
EMBO JOURNAL, 1999, 18 (24) :6873-6879