Solid-phase synthesis of pyrrolidines employing a cyclisation-cleavage strategy

被引：22

作者：

Brown, RCD ^{[1
]}

Fisher, M ^{[1
]}

机构：

[1] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 16期

关键词：

D O I：

10.1039/a904135d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The solid-phase synthesis of several pyrrolidines has been realised utilising imino-Sakurai and palladium-catalysed cyclisation-cleavage reactions as key steps.

引用

页码：1547 / 1548

页数：2

共 14 条

[1] Solid-phase organic reactions III: A review of the literature Nov 96 Dec 97 [J].

Booth, S ;

Hermkens, PHH ;

Ottenheijm, HCJ ;

Rees, DC .

TETRAHEDRON, 1998, 54 (51) :15385-15443

[2]

Brown RCD, 1998, J CHEM SOC PERK T 1, P3293

[3] Linkers for solid-phase synthesis of small molecules: coupling and cleavage techniques [J].

Eggenweiler, HM .

DRUG DISCOVERY TODAY, 1998, 3 (12) :552-560

[4] The United Kingdom Chemical Database Service [J].

Fletcher, DA ;

McMeeking, RF ;

Parkin, D .

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 1996, 36 (04) :746-749

[5] USE OF AN ALLYLIC ANCHOR GROUP AND OF ITS PALLADIUM CATALYZED HYDROSTANNOLYTIC CLEAVAGE IN THE SOLID-PHASE SYNTHESIS OF PROTECTED PEPTIDE-FRAGMENTS [J].

GUIBE, F ;

DANGLES, O ;

BALAVOINE, G ;

LOFFET, A .

TETRAHEDRON LETTERS, 1989, 30 (20) :2641-2644

[6] Linkers for solid phase organic synthesis [J].

James, IW .

TETRAHEDRON, 1999, 55 (16) :4855-4946

[7] Solid-phase synthesis of peptide aminoalkylamides using an allyl linker [J].

Kaljuste, K ;

Unden, A .

TETRAHEDRON LETTERS, 1996, 37 (17) :3031-3034

[8] SOLID-PHASE SYNTHESIS OF PEPTIDES AND GLYCOPEPTIDES ON POLYMERIC SUPPORTS WITH ALLYLIC ANCHOR GROUPS [J].

KUNZ, H ;

DOMBO, B .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1988, 27 (05) :711-713

[9] Synthesis of homoallylic amines via N-acyliminium ion reactions on solid support [J].

Meester, WJN ;

Rutjes, FPJT ;

Hermkens, PHH ;

Hiemstra, H .

TETRAHEDRON LETTERS, 1999, 40 (08) :1601-1604

[10] A [3+2] AND [4+3] CYCLOADDITION APPROACH TO N-HETEROCYCLES VIA PD-CATALYZED TMM REACTIONS WITH IMINES [J].

TROST, BM ;

MARRS, CM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (15) :6636-6645

← 1 2 →