Regenerative medicine for cardiovascular disorders-new milestones: Adult stem cells

被引：18

作者：

Akar, AR ^{[1
]}

Durdu, S

Corapcioglu, T

Ozyurda, U

机构：

[1] Ankara Univ, Sch Med, Heart Ctr, Dept Cardiovasc Surg, TR-06340 Ankara, Turkey

[2] Ankara Univ, Biotechnol Inst, TR-06340 Ankara, Turkey

来源：

ARTIFICIAL ORGANS | 2006年 / 30卷 / 04期

关键词：

cell-based therapy; stem cell; angiogenesis; cardiac regeneration; bone marrow cells; plasticity;

D O I：

10.1111/j.1525-1594.2006.00209.x

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Cardiovascular disorders are the leading causes of mortality and morbidity in the developed world. Cell-based modalities have received considerable scientific attention over the last decade for their potential use in this clinical arena. This review was intended as a brief overview on the subject of therapeutic potential of adult stem cells in cardiovascular medicine with basic science findings and the current status of clinical applications. The historical perspective and basic concepts are reviewed and a description of current applications and potential adverse effects in cardiovascular medicine is given. Future improvements on cell-based therapies will likely provide remarkable improvement in survival and quality of life for millions of patients with cardiovascular disorders.

引用

页码：213 / 232

页数：20

共 184 条

[1]

Akar AR, 2005, BONE MARROW TRANSPL, V35, pS76

[2]

Akar AR, 2005, BONE MARROW TRANSPL, V35, pS47

[3]

AKAR AR, 2004, TURKISH J HAEMATOL, V21, P13

[4] RETROGRADE CARDIOPLEGIA DOES NOT ADEQUATELY PERFUSE THE RIGHT VENTRICLE [J].

ALLEN, BS ;

WINKELMANN, JW ;

HANAFY, H ;

HARTZ, RS ;

BOLLING, KS ;

HAM, J ;

FEINSTEIN, S .

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1995, 109 (06) :1116-1126

[5] Circulating progenitor cells - Search for an identity [J].

Anversa, P ;

Kajstura, J ;

Leri, A .

CIRCULATION, 2004, 110 (20) :3158-3160

[6] Myocyte renewal and ventricular remodelling [J].

Anversa, P ;

Nadal-Ginard, B .

NATURE, 2002, 415 (6868) :240-243

[7] Endothelial progenitor cell capture by stents coated with antibody against CD34 - The HEALING-FIM (healthy endothelial accelerated lining inhibits neointimal growth-first in man) registry [J].

Aoki, J ;

Serruys, PW ;

van Beusekom, H ;

Ong, ATL ;

McFadden, EP ;

Sianos, G ;

van der Giessen, WJ ;

Regar, E ;

de Feyter, PJ ;

Davis, HR ;

Rowland, S ;

Kutryk, MJB .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 45 (10) :1574-1579

[8] Endothelial progenitor cells for postnatal vasculogenesis [J].

Asahara, T ;

Kawamoto, A .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2004, 287 (03) :C572-C579

[9] Isolation of putative progenitor endothelial cells for angiogenesis [J].

Asahara, T ;

Murohara, T ;

Sullivan, A ;

Silver, M ;

vanderZee, R ;

Li, T ;

Witzenbichler, B ;

Schatteman, G ;

Isner, JM .

SCIENCE, 1997, 275 (5302) :964-967

[10] Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization [J].

Asahara, T ;

Masuda, H ;

Takahashi, T ;

Kalka, C ;

Pastore, C ;

Silver, M ;

Kearne, M ;

Magner, M ;

Isner, JM .

CIRCULATION RESEARCH, 1999, 85 (03) :221-228

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