Genetic testing: Psychological aspects and implications

被引:195
作者
Lerman, C
Croyle, RT
Tercyak, KP
Hamann, H
机构
[1] Univ Penn, Ctr Canc, Philadelphia, PA 19104 USA
[2] NCI, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA
[3] Georgetown Univ, Med Ctr, Lombardi Canc Ctr, Washington, DC 20057 USA
[4] Univ Utah, Dept Psychol, Salt Lake City, UT 84112 USA
关键词
D O I
10.1037//0022-006X.70.3.784
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
As the number of genes associated with inherited disease continues to grow, researchers and practitioners in behavioral medicine will encounter complex psychological issues faced by individuals at risk for these diseases. A review of the literature concerning prenatal, carrier, and predictive genetic testing suggests that the severity of psychological risks posed by research-based genetic testing is not great. However, subgroups of individuals with particular psychological traits may be more vulnerable to adverse effects. Available data do not provide evidence that genetic testing promotes changes in health-related behaviors. Thus, although there may be less of a role for mental health professionals in the psychological counseling of genetic testing participants, there is a need for research and practice to facilitate health protective behaviors in response to genetic risk information.
引用
收藏
页码:784 / 797
页数:14
相关论文
共 135 条
  • [1] The effect of an educational intervention on the perceived risk of breast cancer
    Alexander, NE
    Ross, J
    Sumner, W
    Nease, RF
    Littenberg, B
    [J]. JOURNAL OF GENERAL INTERNAL MEDICINE, 1996, 11 (02) : 92 - 97
  • [2] American Academy of Pediatrics, 1997, GUID PER CAR
  • [3] Interest in learning of personal genetic risk for cancer: A general population survey
    Andrykowski, MA
    Munn, RK
    Studts, JL
    [J]. PREVENTIVE MEDICINE, 1996, 25 (05) : 527 - 536
  • [4] [Anonymous], INTREX USERS MANUA 1
  • [5] Armstrong K, 2000, CANCER EPIDEM BIOMAR, V9, P1251
  • [6] Astbury J, 1979, Aust Fam Physician, V8, P595
  • [7] Genetic susceptibility testing in smoking-cessation treatment: One-year outcomes of a randomized trial
    Audrain, J
    Boyd, NR
    Roth, J
    Main, D
    Caporaso, NE
    Lerman, C
    [J]. ADDICTIVE BEHAVIORS, 1997, 22 (06) : 741 - 751
  • [8] ATTITUDES TOWARD DIRECT PREDICTIVE TESTING FOR THE HUNTINGTON DISEASE GENE - RELEVANCE FOR OTHER ADULT-ONSET DISORDERS
    BABUL, R
    ADAM, S
    KREMER, B
    DUFRASNE, S
    WIGGINS, S
    HUGGINS, M
    THEILMANN, J
    BLOCH, M
    HAYDEN, MR
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1993, 270 (19): : 2321 - 2325
  • [9] Stress and genetic testing for disease risk
    Baum, A
    Friedman, AL
    Zakowski, SG
    [J]. HEALTH PSYCHOLOGY, 1997, 16 (01) : 8 - 19
  • [10] Beeson D, 1979, Birth Defects Orig Artic Ser, V15, P191