Degree of facial and body terminal hair growth in unselected black and white women: Toward a populational definition of hirsutism

被引:164
作者
DeUgarte, CM
Woods, KS
Bartolucci, AA
Azziz, R
机构
[1] Cedars Sinai Med Ctr, Dept Obstet & Gynecol, Los Angeles, CA 90048 USA
[2] Univ Calif Los Angeles, Dept Obstet & Gynecol, David Geffen Sch Med, Los Angeles, CA 90095 USA
[3] Univ Alabama Birmingham, Dept Biostat & Biomath, Birmingham, AL 35294 USA
[4] Univ Alabama Birmingham, Dept Obstet & Gynecol, Birmingham, AL 35294 USA
关键词
D O I
10.1210/jc.2004-2301
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Context: Hirsutism (i.e. facial and body terminal hair growth in a male-like pattern in women) is the principal clinical sign of hyperandrogenism, although its definition remains unclear. Objective: The purposes of the present study were to define 1) the degree of facial and body terminal hair, as assessed by the modified Ferriman-Gallwey (mFG) score, in unselected women from the general population; 2) the effect of race ( Black and White) on the same; and 3) the normative cutoff values. Design and Setting: We conducted a prospective observational study at a tertiary academic medical center. Patients/Participants: Participants included 633 unselected White ( n = 283) and Black ( n = 350) women presenting for a preemployment physical exam. Interventions: Interventions included history and physical examination. Main Outcome Measures: Terminal body hair growth was assessed using the mFG scoring system; nine body areas were scored from 0 - 4 for terminal hair growth distribution. Results: The mFG scores were not normally distributed; although cluster analysis failed to identify a natural cutoff value or clustering of the population, principal component and univariate analyses denoted two nearly distinct clusters that occurred above and below an mFG value of 2, with the bulk of the scores below. Overall, an mFG score of at least 3 was observed in 22.1% of all subjects (i.e. the upper quartile); of these subjects, 69.3% complained of being hirsute, compared with 15.8% of women with an mFG score below this value, and similar to the proportion of women with an mFG score of at least 8 who considered themselves to be hirsute (70.0%). Overall, there were no significant differences between Black and White women. Conclusions: Our data indicate that the prevalence and degree of facial and body terminal hair growth, as assessed by the mFG score, is similar in Black and White women and that an mFG of at least 3 signals the population of women whose hair growth falls out of the norm.
引用
收藏
页码:1345 / 1350
页数:6
相关论文
共 24 条
[1]
Androgen excess in women: Experience with over 1000 consecutive patients [J].
Azziz, R ;
Sanchez, LA ;
Knochenhauer, ES ;
Moran, C ;
Lazenby, J ;
Stephens, KC ;
Taylor, K ;
Boots, LR .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (02) :453-462
[2]
The prevalence and features of the polycystic ovary syndrome in an unselected population [J].
Azziz, R ;
Woods, KS ;
Reyna, R ;
Key, TJ ;
Knochenhauer, ES ;
Yildiz, BO .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (06) :2745-2749
[3]
THE TREATMENT OF HYPERANDROGENISM WITH ORAL-CONTRACEPTIVES [J].
AZZIZ, R ;
GAY, F .
SEMINARS IN REPRODUCTIVE ENDOCRINOLOGY, 1989, 7 (03) :246-254
[4]
Estimation of average treatment effects based on propensity scores [J].
Becker, Sascha O. ;
Ichino, Andrea .
STATA JOURNAL, 2002, 2 (04) :358-377
[5]
The aesthetics of follicular transplantation [J].
Bernstein, RM ;
Rassman, WR .
DERMATOLOGIC SURGERY, 1997, 23 (09) :785-799
[6]
DOES ETHNICITY INFLUENCE THE PREVALENCE OF ADRENAL HYPERANDROGENISM AND INSULIN RESISTANCE IN POLYCYSTIC-OVARY-SYNDROME [J].
CARMINA, E ;
KOYAMA, T ;
CHANG, L ;
STANCZYK, FZ ;
LOBO, RA .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1992, 167 (06) :1807-1812
[7]
DERKSEN J, 1993, BRIT J DERMATOL, V128, P259
[8]
CLINICAL ASSESSMENT OF BODY HAIR GROWTH IN WOMEN [J].
FERRIMAN, D ;
GALLWEY, JD .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1961, 21 (11) :1440-+
[9]
THE ETIOLOGY OF OLIGOMENORRHEA AND OR HIRSUTIES - A STUDY OF 467 PATIENTS [J].
FERRIMAN, D ;
PURDIE, AW .
POSTGRADUATE MEDICAL JOURNAL, 1983, 59 (687) :17-20
[10]
Gavin JR, 1997, DIABETES CARE, V20, P1183