Production of tunable, monochromatic X-rays by the Vanderbilt free-electron laser

被引:15
作者
Carroll, FE [1 ]
Waters, JW [1 ]
Traeger, RH [1 ]
Mendenhall, MH [1 ]
Clark, WW [1 ]
Brau, CA [1 ]
机构
[1] Vanderbilt Univ, Med Ctr, Dept Radiol & Radiol Sci, Nashville, TN 37232 USA
来源
FREE-ELECTRON LASER CHALLENGES II | 1999年 / 3614卷
关键词
monochromatic X-rays; free-electron lasers; breast cancer; inverse compton scattering;
D O I
10.1117/12.352661
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Sustained/long duration X-ray output has been demonstrated emanating from the monochromatic X-ray beamline of the Vanderbilt Free-Electron Laser. Tunable, pulsed monochromatic X-rays ranging in energy from 14 - 18 keV are produced by inverse Compton scattering created by the counter propagation of the FEL e-beam and its own infrared beam. These beams are focused and optimized at an interaction zone between the linac and the wiggler where they are brought into coalignment. The X-rays produced exit the beamline through a beryllium window and are directed onto mosaic crystals which divert the beam to an imaging laboratory on the floor above the vault. The initial application of these X-rays is directed toward human imaging, specifically for the diagnosis of breast diseases including cancer. The characteristics of the X-rays are such that they can be used in standard geometry monochromatic imaging, CT like images of the breast using a rotating mosaic crystal "optic", time-of-flight imaging and phase contrast images. Eventual extension to other portions of the body, cell biology and material sciences are already anticipated.
引用
收藏
页码:139 / 146
页数:8
相关论文
共 15 条
  • [1] New autocorrelation technique for the IR FEL optical pulsewidth measurements
    Amirmadhi, F
    Brau, C
    Becker, K
    Mendenhall, M
    [J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1996, 375 (1-3) : 427 - 429
  • [2] BRAU CA, 1992, NUCL INSTRUM METH A, V319, P47, DOI 10.1016/0168-9002(92)90529-D
  • [3] BRAU CA, 1993, NUCL INSTRUM METH A, V331, P4
  • [4] BRAU CA, 1993, NUCL INSTRUM METH A, V341, P21
  • [5] Positron production in multiphoton light-by-light scattering
    Burke, DL
    Field, RC
    HortonSmith, G
    Spencer, JE
    Walz, D
    Berridge, SC
    Bugg, WM
    Shmakov, K
    Weidemann, AW
    Bula, C
    McDonald, KT
    Prebys, EJ
    Bamber, C
    Boege, SJ
    Koffas, T
    Kotseroglou, T
    Melissinos, AC
    Meyerhofer, DD
    Reis, DA
    Raggk, W
    [J]. PHYSICAL REVIEW LETTERS, 1997, 79 (09) : 1626 - 1629
  • [6] ATTENUATION OF MONOCHROMATIC X-RAYS BY NORMAL AND ABNORMAL BREAST TISSUES
    CARROLL, FE
    WATERS, JW
    ANDREWS, WW
    PRICE, RR
    PICKENS, DR
    WILLCOTT, R
    TOMPKINS, P
    ROOS, C
    PAGE, D
    REED, G
    UEDA, A
    BAIN, R
    WANG, P
    BASSINGER, M
    [J]. INVESTIGATIVE RADIOLOGY, 1994, 29 (03) : 266 - 272
  • [7] NEAR-MONOCHROMATIC X-RAY-BEAMS PRODUCED BY THE FREE-ELECTRON LASER AND COMPTON BACKSCATTER
    CARROLL, FE
    WATERS, JW
    PRICE, RR
    BRAU, CA
    ROOS, CF
    TOLK, NH
    PICKENS, DR
    STEPHENS, WH
    [J]. INVESTIGATIVE RADIOLOGY, 1990, 25 (05) : 465 - 471
  • [8] Dong W W, 1994, J Xray Sci Technol, V4, P346, DOI [10.1016/S0895-3996(05)80051-5, 10.3233/XST-1994-4409]
  • [9] TIME-GATED IMAGING WITH AN ULTRASHORT-PULSE, LASER-PRODUCED-PLASMA X-RAY SOURCE
    GORDON, CL
    YIN, GY
    LEMOFF, BE
    BELL, PM
    BARTY, CPJ
    [J]. OPTICS LETTERS, 1995, 20 (09) : 1056 - 1058
  • [10] X-RAY CHARACTERIZATION OF NORMAL AND NEOPLASTIC BREAST TISSUES
    JOHNS, PC
    YAFFE, MJ
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 1987, 32 (06) : 675 - 695