Mixed Dyslipidemia, Metabolic Syndrome, Diabetes Mellitus, and Cardiovascular Disease: Clinical Implications

被引：69

作者：

Cannon, Christopher P. ^{[1
,2
]}

机构：

[1] Brigham & Womens Hosp, Div Cardiovasc, TIMI Study Grp, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2008年 / 102卷 / 12A期

关键词：

D O I：

10.1016/j.amjcard.2008.09.067

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Metabolic syndrome and type 2 diabetes mellitus are individually associated with increased cardiovascular risk; furthermore, the combination of metabolic syndrome with diabetes accentuates this risk. An atherogenic dyslipidemia characterized by elevated triglycerides, low high-density lipoprotein cholesterol, or both conditions is a key modifiable risk factor associated with both conditions. As the development of this atherogenic mixed dyslipidemia precedes the onset of overt glycemia and the clinical diagnosis of diabetes, early effective intervention is recommended to reduce the risk of premature cardiovascular disease morbidity and mortality. (c) 2008 Elsevier Inc. All rights reserved. (Am J Cardiol 2008;102[suppl]:5L-9L)

引用

页码：5L / 9L

页数：5

共 36 条

[1]

International Diabetes Federation: a consensus on Type 2 diabetes prevention [J].

Alberti, K. G. M. M. ;

Zimmet, P. ;

Shaw, J. .

DIABETIC MEDICINE, 2007, 24 (05) :451-463

[2]

NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older [J].

Alexander, CM ;

Landsman, PB ;

Teutsch, SM ;

Haffner, SM .

DIABETES, 2003, 52 (05) :1210-1214

[3]

[Anonymous], 2004, INT TXB DIABETES MEL

[4]

Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women [J].

Bansal, Sandeep ;

Buring, Julie E. ;

Rifai, Nader ;

Mora, Samia ;

Sacks, Frank M. ;

Ridker, Paul M. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 298 (03) :309-316

[5]

Metabolic syndrome and the risk of cardiovascular disease in older adults [J].

Butler, J ;

Rodondi, N ;

Zhu, YW ;

Figaro, K ;

Fazio, S ;

Vaughan, DE ;

Satterfield, S ;

Newman, AB ;

Goodpaster, B ;

Bauer, DC ;

Holvoet, P ;

Harris, TB ;

de Rekeneire, N ;

Rubin, S ;

Ding, JZ ;

Kritchevsky, SB .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 47 (08) :1595-1602

[6]

Low-density lipoprotein size, pravastatin treatment, and coronary events [J].

Campos, H ;

Moye, LA ;

Glasser, SP ;

Stampfer, MJ ;

Sacks, FM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 286 (12) :1468-1474

[7]

Cardiovascular disease: much more aggressive in patients with type 2 diabetes. [J].

Chiquette E. ;

Chilton R. .

Current Atherosclerosis Reports, 2002, 4 (2) :134-142

[8]

Aggregation of features of the metabolic syndrome is associated with increased prevalence of chronic complications in Type 2 diabetes [J].

Costa, LA ;

Canani, LH ;

Lisbôa, HRK ;

Tres, GS ;

Gross, JL .

DIABETIC MEDICINE, 2004, 21 (03) :252-255

[9]

Prevalence of the metabolic syndrome among US adults - Findings from the Third National Health and Nutrition Examination Survey [J].

Ford, ES ;

Giles, WH ;

Dietz, WH .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 287 (03) :356-359

[10]

Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome - A summary of the evidence [J].

Ford, ES .

DIABETES CARE, 2005, 28 (07) :1769-1778

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