The history and basic science development of soy isoflavones

被引：16

作者：

Setchell, Kenneth D. R. ^{[1
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Dept Pathol & Lab Med, 3333 Burnet Ave, Cincinnati, OH 45229 USA

来源：

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY | 2017年 / 24卷 / 12期

基金：

英国医学研究理事会; 美国国家卫生研究院;

关键词：

Equol; Genistein; Isoflavones; Menopause; Phytoestrogens; Soy; EQUOL-PRODUCER STATUS; C-REACTIVE PROTEIN; ESTROGEN-RECEPTOR-ALPHA; LOW-DENSITY-LIPOPROTEIN; DAIDZEIN-METABOLIZING PHENOTYPES; INFLAMMATION-SENSITIVE PROTEINS; CARDIOVASCULAR-DISEASE RISK; HORMONE REPLACEMENT THERAPY; MENOPAUSAL HOT FLASHES; BREAST-CANCER RISK;

D O I：

10.1097/GME.0000000000001018

中图分类号：

R71 [妇产科学];

学科分类号：

100211 [妇产科学];

摘要：

This review summarizes the 2016 NAMS/Pfizer-Wulf H. Utian Endowed Lecture that focused on the history and basic science of soy isoflavones. Described is a personal perspective of the background and history that led to the current interest in soy and isoflavones with a specific focus on the role that soy isoflavones play in the health of postmenopausal women. This overview covers the metabolism and physiological behavior of isoflavones, their biological properties that are of potential relevance to aging, issues related to the safety of soy isoflavones, and the role of the important intestinally derived metabolite S-(-)equol.

引用

页码：1338 / 1350

页数：13

共 233 条

[1]

EFFECTS OF ISOFLAVONES ON THE SKIN OF POSTMENOPAUSAL WOMEN: A PILOT STUDY [J].

Accorsi-Neto, Alfeu ;

Haidar, Mauro ;

Simoes, Ricardo ;

Simoes, Manuel ;

Soares-, Jose, Jr. ;

Baracat, Edmund .

CLINICS, 2009, 64 (06) :505-510

[2]

DIETARY PHYTO-ESTROGENS AND THE MENOPAUSE IN JAPAN [J].

ADLERCREUTZ, H ;

HAMALAINEN, E ;

GORBACH, S ;

GOLDIN, B .

LANCET, 1992, 339 (8803) :1233-1233

[3]

Significant inverse association of equol-producer status with coronary artery calcification but not dietary isoflavones in healthy Japanese men [J].

Ahuja, Vasudha ;

Miura, Katsuyuki ;

Vishnu, Abhishek ;

Fujiyoshi, Akira ;

Evans, Rhobert ;

Zaid, Maryam ;

Miyagawa, Naoko ;

Hisamatsu, Takashi ;

Kadota, Aya ;

Okamura, Tomonori ;

Ueshima, Hirotsugu ;

Sekikawa, Akira .

BRITISH JOURNAL OF NUTRITION, 2017, 117 (02) :260-266

[4]

Comparisons of percent equol producers between prostate cancer patients and controls: Case-controlled studies of isoflavones in Japanese, Korean and American residents [J].

Akaza, H ;

Miyanaga, N ;

Takashima, N ;

Naito, S ;

Hirao, Y ;

Tsukamoto, T ;

Fujioka, T ;

Mori, M ;

Kim, WJ ;

Song, JM ;

Pantuck, AJ .

JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2004, 34 (02) :86-89

[5]

Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein [J].

Allred, CD ;

Ju, YH ;

Allred, KF ;

Chang, J ;

Helferich, WG .

CARCINOGENESIS, 2001, 22 (10) :1667-1673

[6]

American Institute for Cancer Research (AICR), 2012, SOY IS SAF BREAST CA

[7]

METAANALYSIS OF THE EFFECTS OF SOY PROTEIN-INTAKE ON SERUM-LIPIDS [J].

ANDERSON, JW ;

JOHNSTONE, BM ;

COOKNEWELL, ME .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (05) :276-282

[8]

Anderson JW, 1999, AM J CLIN NUTR, V70, p464S, DOI 10.1093/ajcn/70.3.464s

[9]

[Anonymous], 1999, Fed Regist, V64, P57700

[10]

Antioxidant activities of isoflavones and their biological metabolites in a liposomal system [J].

Arora, A ;

Nair, MG ;

Strasburg, GM .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1998, 356 (02) :133-141

← 1 2 3 4 5 6 7 8 9 10 →