The invasion-associated type-III protein secretion system in Salmonella - A review

被引：147

作者：

Collazo, CM ^{[1
]}

Galan, JE ^{[1
]}

机构：

[1] SUNY STONY BROOK,SCH MED,DEPT MOL GENET & MICROBIOL,STONY BROOK,NY 11794

来源：

GENE | 1997年 / 192卷 / 01期

关键词：

bacterial pathogenesis; bacteria host cell interaction; virulence; pathogenicity island; chaperone;

D O I：

10.1016/S0378-1119(96)00825-6

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The genetic determinants that confer upon Salmonella the ability to enter non-phagocytic cells are largely encoded in a pathogenicity island located at centisome 63 of the bacterial chromosome. Molecular genetic analysis has revealed that this region encodes a specialized protein secretion system that mediates the export and/or translocation of putative signaling proteins into the host cell. This protein secretion system, which has been termed type III or contact-dependent, has also been identified in other plant and animal pathogens that have, in common, the ability to interact with eukaryotic host cells in an intimate manner. (C) 1997 Elsevier Science B.V.

引用

页码：51 / 59

页数：9

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