Comorbidities and Systemic Effects of Chronic Obstructive Pulmonary Disease

被引：151

作者：

Choudhury, Gourab ^{[1
]}

Rabinovich, Roberto

Mac, William

机构：

[1] Queens Med Res Inst, ELEGI, Edinburgh EH16 4TJ, Midlothian, Scotland

来源：

CLINICS IN CHEST MEDICINE | 2014年 / 35卷 / 01期

关键词：

Chronic obstructive pulmonary disease; Comorbidities; Systemic effects; Inflammation; Management strategy; BONE-MINERAL DENSITY; AIR-FLOW OBSTRUCTION; CHRONIC INTERMITTENT HYPOXIA; PERIPHERAL MUSCLE WEAKNESS; STEROID-INDUCED MYOPATHY; IMPAIRED LUNG-FUNCTION; ALL-CAUSE MORTALITY; BODY-MASS INDEX; FAT-FREE-MASS; HEART-FAILURE;

D O I：

10.1016/j.ccm.2013.10.007

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

100201 [内科学];

摘要：

Although primarily a lung disease, chronic obstructive pulmonary disease (CORD) is now recognized to have extrapulmonary effects on distal organs, the so-called systemic effects and comorbidities of CORD. Skeletal muscle dysfunction, nutritional abnormalities including weight loss, cardiovascular complications, metabolic complications, and osteoporosis, among others, are all well-recognized associations in CORD. These extrapulmonary effects add to the burden of mortality and morbidity in COPD and therefore should be actively looked for, assessed, and treated.

引用

页码：101 / +

页数：31

共 261 条

[1]

Airflow obstruction, lung function, and risk of incident heart failure: the Atherosclerosis Risk in Communities (ARIC) study [J].

Agarwal, Sunil K. ;

Heiss, Gerardo ;

Barr, R. Graham ;

Chang, Patricia P. ;

Loehr, Laura R. ;

Chambless, Lloyd E. ;

Shahar, Eyal ;

Kitzman, Dalane W. ;

Rosamond, Wayne D. .

EUROPEAN JOURNAL OF HEART FAILURE, 2012, 14 (04) :414-422

[2]

Agusti AG, 2005, P AM THORAC SOC, V2, P371

[3]

Systemic effects of chronic obstructive pulmonary disease [J].

Agustí, AGN ;

Noguera, A ;

Sauleda, J ;

Sala, E ;

Pons, J ;

Busquets, X .

EUROPEAN RESPIRATORY JOURNAL, 2003, 21 (02) :347-360

[4]

Agusti Alvar, 2007, Proc Am Thorac Soc, V4, P522, DOI 10.1513/pats.200701-004FM

[5]

Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype [J].

Agusti, Alvar ;

Edwards, Lisa D. ;

Rennard, Stephen I. ;

MacNee, William ;

Tal-Singer, Ruth ;

Miller, Bruce E. ;

Vestbo, Jorgen ;

Lomas, David A. ;

Calverley, Peter M. A. ;

Wouters, Emiel ;

Crim, Courtney ;

Yates, Julie C. ;

Silverman, Edwin K. ;

Coxson, Harvey O. ;

Bakke, Per ;

Mayer, Ruth J. ;

Celli, Bartolome .

PLOS ONE, 2012, 7 (05)

[6]

Characterisation of COPD heterogeneity in the ECLIPSE cohort [J].

Agusti, Alvar ;

Calverley, Peter M. A. ;

Celli, Bartolome ;

Coxson, Harvey O. ;

Edwards, Lisa D. ;

Lomas, David A. ;

MacNee, William ;

Miller, Bruce E. ;

Rennard, Steve ;

Silverman, Edwin K. ;

Tal-Singer, Ruth ;

Wouters, Emiel ;

Yates, Julie C. ;

Vestbo, Jorgen .

RESPIRATORY RESEARCH, 2010, 11

[7]

Agusti Alvar G N, 2005, Proc Am Thorac Soc, V2, P367, DOI 10.1513/pats.200504-026SR

[8]

Circulating monocytes from healthy individuals and COPD patients [J].

Aldonyte, R ;

Jansson, L ;

Piitulainen, E ;

Janciauskiene, S .

RESPIRATORY RESEARCH, 2003, 4 (11)

[9]

ALESSANDRI C, 1994, THROMB HAEMOSTASIS, V72, P343

[10]

Peripheral muscle endurance and the oxidative profile of the quadriceps in patients with COPD [J].

Allaire, J ;

Maltais, F ;

Doyon, JF ;

Noël, M ;

LeBlanc, P ;

Carrier, G ;

Simard, C ;

Jobin, J .

THORAX, 2004, 59 (08) :673-678

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