Beneficial Effects of Traditional Chinese Medicine on the Treatment of Osteoporosis on Ovariectomised Rat Models

被引:47
作者
Rufus, Pamela [1 ]
Mohamed, Norazlina [1 ]
Shuid, Ahmad Nazrun [1 ]
机构
[1] Univ Kebangsaan Malaysia, Dept Pharmacol, Fac Med, Kuala Lumpur 50300, Malaysia
关键词
Bone disorder; herbal drugs; hormone replacement therapy; osteoporosis; traditional Chinese medicine; INDUCED BONE LOSS; HACHIMI-JIO-GAN; OSTEOCLAST FORMATION; HERBAL PREPARATION; EXTRACT; CELLS; WOMEN; WAN;
D O I
10.2174/1389450114666131220160357
中图分类号
R9 [药学];
学科分类号
100702 [药剂学];
摘要
Osteoporosis is a metabolic bone disorder that affects both men and women worldwide. It causes low bone mass and therefore increases bone susceptibility to fracture when bone undergoes a minor trauma. Lack of estrogen is the principal cause of osteoporosis. Estrogen, calcium, calcitonin, vitamin D and several antioxidants help in the prevention of osteoporosis. In order to effectively treat osteoporosis, there has been an extended research on the biological activities of traditional medicines since synthetic medicines possess several side effects that reduce their efficacy. Therefore, there is a need to develop new treatment alternatives for osteoporosis. This review centres on the scientific researches carried out on the evaluation of Chinese traditional medicines in the treatment of osteoporosis. Various plants like Achyranthes bidentata, Davallia formosana, polygonatum sibiricum, Cibotium barometz, Er-Zhi-Wan, Curculigo orchioides and a combined treatment of Hachimi-jio-gan (Ba-Wei-Di-Huang-Wan) with alendronate proved active in preventing post-menopausal osteoporosis.
引用
收藏
页码:1689 / 1693
页数:5
相关论文
共 40 条
[1]
Benefits of hormone replacement therapy in postmenopausal women [J].
Canderelli, Richard ;
Leccesse, Lisa A. ;
Miller, Nancy L. .
JOURNAL OF THE AMERICAN ACADEMY OF NURSE PRACTITIONERS, 2007, 19 (12) :635-641
[2]
Cao PD, 2008, MAURITUS, V59, P373
[3]
A traditional Chinese herbal preparation, Er-Zhi-Wan, prevent ovariectomy-induced osteoporosis in rats [J].
Cheng, Min ;
Wang, Qingwei ;
Fan, Yinke ;
Liu, Xueying ;
Wang, Lu ;
Xie, Renmin ;
Ho, Charlene C. ;
Sun, Wenji .
JOURNAL OF ETHNOPHARMACOLOGY, 2011, 138 (02) :279-285
[4]
The molecular inflammatory process in aging [J].
Chung, Hae Young ;
Sung, Bokyung ;
Jung, Kyung Jin ;
Zou, Yani ;
Yu, Byung Pal .
ANTIOXIDANTS & REDOX SIGNALING, 2006, 8 (3-4) :572-581
[5]
A novel bone substitute composite composed of tricalcium phosphate, gelatin and drynaria fortunei herbal extract [J].
Dong, Guo-Chung ;
Chen, Hueih Min ;
Yao, Chun-Hsu .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2008, 84A (01) :167-177
[6]
Severity of vertebral fracture reflects deterioration of bone microarchitecture [J].
Genant, H. K. ;
Delmas, P. D. ;
Chen, P. ;
Jiang, Y. ;
Eriksen, E. F. ;
Dalsky, G. P. ;
Marcus, R. ;
San Martin, J. .
OSTEOPOROSIS INTERNATIONAL, 2007, 18 (01) :69-76
[7]
Secondary osteoporosis - Diagnostic considerations [J].
Harper, KD ;
Weber, TJ .
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 1998, 27 (02) :325-+
[8]
Osteoprotective effect of extract from Achyranthes bidentata in ovariectomized rats [J].
He, Cui-Cui ;
Hui, Rong-Rong ;
Tezuka, Yasuhiro ;
Kadota, Shigetoshi ;
Li, Jian-Xin .
JOURNAL OF ETHNOPHARMACOLOGY, 2010, 127 (02) :229-234
[9]
Huaye C, 2012, J ETHNOPHARMACO, V142, P80
[10]
Hachimijiogan (Ba-Wei-Di-Huang-Wan), a herbal medicine, improves unbalance of calcium metabolism in aged rats [J].
Ikeda, Ryuji ;
Mizoguchi, Kazushige .
JOURNAL OF ETHNOPHARMACOLOGY, 2009, 124 (02) :176-181