Epidemiology of abnormal glucose metabolism in a country facing its epidemic: SAUDI-DM study

被引:101
作者
Al-Rubeaan, Khalid [5 ]
Al-Manaa, Hamad A. [6 ]
Khoja, Tawfik A. [7 ]
Ahmad, Najlaa A. [1 ]
Al-Sharqawi, Ahmad H. [1 ]
Siddiqui, Khalid [2 ]
Alnaqeb, Dehkra [3 ]
Aburisheh, Khaled H. [5 ]
Youssef, Amira M. [4 ]
Al-Batel, Abdullah [8 ]
Alotaibi, Metib S. [5 ]
Al-Gamdi, Ali A. [5 ]
机构
[1] King Saud Univ, Dept Biostat, Riyadh, Saudi Arabia
[2] King Saud Univ, Strateg Ctr Diabet Res, Riyadh, Saudi Arabia
[3] King Saud Univ, Res Dept, Riyadh, Saudi Arabia
[4] King Saud Univ, Registry Dept, Riyadh, Saudi Arabia
[5] King Saud Univ, Univ Diabet Ctr, Riyadh, Saudi Arabia
[6] Minist Hlth, Riyadh, Saudi Arabia
[7] Gulf Cooperat Council, Riyadh, Saudi Arabia
[8] Cent Dept Stat & Informat, Riyadh, Saudi Arabia
关键词
abnormal glucose metabolism; age-specific prevalence; diabetes mellitus; Saudi Arabia; IMPAIRED FASTING GLUCOSE; INCIDENT DIABETES-MELLITUS; RISK-FACTORS; CARDIOVASCULAR-DISEASE; URBAN-POPULATION; HIGH PREVALENCE; PLASMA-GLUCOSE; OBESITY; TOLERANCE; SMOKING;
D O I
10.1111/1753-0407.12224
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
BackgroundSaudi Arabia is a community thrilled by sudden social and economical changes, leading to a sharp increase in the prevalence of abnormal glucose metabolism. Age-specific diabetes and impaired fasting glucose prevalence is the focus of this study with the expected risk factors. MethodsA nationwide, household, randomized, population based cohort of 18034 participants aged 30 years was selected to test for abnormal glucose metabolism using fasting plasma glucose (FPG) according to American Diabetes Association (ADA) criteria. ResultsThe prevalence of diabetes was 25.4% with 40.3% being unaware of their disease, while impaired fasting glucose (IFG) affected 25.5% of the total sample. IFG to diabetes ratio was one in this study, decreasing with age and increasing with body weight. Age 45 years, hypertension, history of gestational diabetes mellitus (GDM), and high triglycerides are the strongest risk factors in diabetic patients, while history of GDM, dyslipidemia, obesity, and high triglycerides are the most significant risk factors in IFG participants. ConclusionsAbnormal glucose metabolism has reached an epidemic level in this society, where half of adults and older are affected. Risk factors are behind this epidemic and the quick shift from IFG to diabetes in this society. ?? ?????????????????????????,??????????????????????????????????????????????????????? ???????????????????????????,???18034??? 30?????,??????????????????(FPG)????????????? ?????????25.4%,??40.3%??????????,?????????????????25.5%????????????????????1,?????????????,?????????????????? 45??????????????????????????????,?GDM??????????????????????????????????? ????????????????????????,????????????????????????????????????????,??????????????????
引用
收藏
页码:622 / 632
页数:11
相关论文
共 47 条
[1]
Genetic dilsorders in the Arab world [J].
Al-Gazali, Lihadh ;
Hamamy, Hanan ;
Al-Arrayad, Shaikha .
BMJ-BRITISH MEDICAL JOURNAL, 2006, 333 (7573) :831-834B
[2]
Al-Hazzaa H M, 2004, East Mediterr Health J, V10, P663
[3]
Physical activity, sedentary behaviors and dietary habits among Saudi adolescents relative to age, gender and region [J].
Al-Hazzaa, Hazzaa M. ;
Abahussain, Nada A. ;
Al-Sobayel, Hana I. ;
Qahwaji, Dina M. ;
Musaiger, Abdulrahman O. .
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, 2011, 8
[4]
Al-Nozha MM, 2007, SAUDI MED J, V28, P559
[5]
Al-Nozha MM, 2005, SAUDI MED J, V26, P1918
[6]
Al-Nozha MM, 2004, SAUDI MED J, V25, P1603
[7]
Prevalence of Type 2 Diabetes in the States of The Co-Operation Council for the Arab States of the Gulf: A Systematic Review [J].
Alhyas, Layla ;
McKay, Ailsa ;
Majeed, Azeem .
PLOS ONE, 2012, 7 (08)
[8]
Amer Diabet Assoc, 2011, DIABETES CARE, V34, pS11, DOI [10.2337/dc11-S062, 10.2337/dc14-S081, 10.2337/dc11-S011, 10.2337/dc13-S067, 10.2337/dc12-s011, 10.2337/dc10-S011, 10.2337/dc10-S062, 10.2337/dc13-S011, 10.2337/dc12-s064]
[9]
Overweight and obesity and their relation to dietary habits and socio-demographic characteristics among male primary school children in Al-Hassa, Kingdom of Saudi Arabia [J].
Amin, Tarek Tawfik ;
Al-Sultan, Ali Ibrahim ;
Ali, Ayub .
EUROPEAN JOURNAL OF NUTRITION, 2008, 47 (06) :310-318
[10]
SUSPECTED SYNERGISM BETWEEN CONSANGUINITY AND FAMILIAL AGGREGATION IN TYPE-2 DIABETES-MELLITUS IN SAUDI-ARABIA [J].
ANOKUTE, CC .
JOURNAL OF THE ROYAL SOCIETY OF HEALTH, 1992, 112 (04) :167-169