Synthesis of biaryls using nickel-catalyzed [2+2+2] cocyclization

被引：89

作者：

Sato, Y ^{[1
]}

Ohashi, K ^{[1
]}

Mori, M ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 28期

关键词：

biaryl; 2+2+2] cocyclization; cotrimerization; cycloaddition; nickel catalyst;

D O I：

10.1016/S0040-4039(99)00945-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methods of synthesizing biaryls using nickel-catalyzed [2+2+2] cocyclization were developed. Two ways for the synthesis of biaryl using [2+2+2] cocyclization were investigated: one method is that biaryls synthesized from alkyne having a phenyl group and 2 equivalents of acetylene, and the other method is that those were synthesized from alpha,omega-diyne having a phenyl group at an alpha-position and acetylene. The yield is good in each case. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：5231 / 5234

页数：4

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