Enhancement of optoacoustic tissue contrast with absorbing nanoparticles

被引：48

作者：

Oraevsky, AA ^{[1
]}

Karabutov, AA ^{[1
]}

Savateeva, EV ^{[1
]}

机构：

[1] Univ Texas, Med Branch, Ctr Biomed Engn, Optoacoust Imaging & Spectroscopy Lab, Galveston, TX 77550 USA

来源：

HYBRID AND NOVEL IMAGING AND NEW OPTICAL INSTRUMENTATION FOR BIOMEDICAL APPLICATIONS | 2001年 / 4434卷

关键词：

optoacoustic nonlinearity; contrast agent; cancer; plasmon resonance; nanoparticles; nanotubes; optoacoustic tomography;

D O I：

10.1117/12.446693

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Laser induced phase transition in the water surrounding absorbing nanoparticle results in dramatic enhancement of the thermoacoustic efficiency and excitation of high-amplitude pressure waves. Feasibility study was performed in tissue phantoms. Experiments supported with theoretical model demonstrated possibility to increase the efficiency of optoacoustic generation in tissue up to two orders of magnitude by application of absorbing carbon and gold nanoparticles.

引用

页码：60 / 69

页数：10

共 27 条

[1]

*AM LAS I, 2000, Z13612000 ANSI

[2] Photoacoustic shock generation in carbon suspensions [J].