Marijuana-positive urine test results from consumption of hemp seeds in food products

被引:26
作者
Fortner, N
Fogerson, R
Lindman, D
Iversen, T
Armbruster, D
机构
[1] PharmChem Laboratories, Inc., Menlo Park, CA 94025
关键词
D O I
10.1093/jat/21.6.476
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Commercially available snack bars and other foodstuffs prepared from pressed hemp seeds were ingested by volunteers. Urine specimens were collected for 24 h after ingestion of the foodstuffs containing hemp seeds and tested for marijuana using an EMIT immunoassay and gas chromatography- mass spectrometry (GC-MS). Specimens from individuals who ate one hemp seed bar demonstrated little marijuana immunoreactivity, and only one specimen screened positive at a 20-ng/mL cutoff. Specimens from individuals who ate two hemp seed bars showed increased immunoreactivity, and five specimens screened positive at a 20-ng/mL cutoff. A single specimen yielded a quantitative GC-MS value (0.6 ng/mL), but it failed to meet reporting criteria. Several specimens from individuals who ate three cookies made from hemp seed flour and butter screened positive at both 50- and 20-ng/mL cutoffs. Two specimens produced quantitative GC-MS values (0.7 and 3.1 ng/mL), but they failed to meet reporting criteria. Several specimens also tested positive with an FDA-approved on-site marijuana-screening device. Hemp seeds similar to those used in the foodstuffs did not demonstrate the presence of marijuana when tested by GC-MS. In this study, ingestion of hemp seed food products resulted in urine specimens that screened positive for marijuana. No specimens gave a GC-MS quantitative value above the limit of detection for marijuana.
引用
收藏
页码:476 / 481
页数:6
相关论文
共 8 条
[1]  
Cone E J, 1990, NIDA Res Monogr, V99, P88
[2]   MARIJUANA-LACED BROWNIES - BEHAVIORAL-EFFECTS, PHYSIOLOGIC EFFECTS, AND URINALYSIS IN HUMANS FOLLOWING INGESTION [J].
CONE, EJ ;
JOHNSON, RE ;
PAUL, BD ;
MELL, LD ;
MITCHELL, J .
JOURNAL OF ANALYTICAL TOXICOLOGY, 1988, 12 (04) :169-175
[3]   HUMAN URINARY-EXCRETION PROFILE AFTER SMOKING AND ORAL-ADMINISTRATION OF [C-14] DELTA-1-TETRAHYDROCANNABINOL [J].
JOHANSSON, E ;
GILLESPIE, HK ;
HALLDIN, MM .
JOURNAL OF ANALYTICAL TOXICOLOGY, 1990, 14 (03) :176-180
[4]   FORENSIC ASPECTS OF THE METABOLISM AND EXCRETION OF CANNABINOIDS FOLLOWING ORAL INGESTION OF CANNABIS RESIN [J].
LAW, B ;
MASON, PA ;
MOFFAT, AC ;
GLEADLE, RI ;
KING, LJ .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 1984, 36 (05) :289-294
[5]   A RANDOM-WALK THROUGH A CANNABIS FIELD [J].
MECHOULAM, R ;
DEVANE, WA ;
BREUER, A ;
ZAHALKA, J .
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1991, 40 (03) :461-464
[6]  
Peat M.A., 1989, ADV ANAL TOXICOLOGY, V2, P186
[7]  
PEREZREY.M, 1973, CLIN PHARMACOL THER, V14, P48
[8]  
REGENSCHEIDT P, 1996, 34 TIAFT M AUG