Current issues in delivering DCs for immunotherapy

被引：19

作者：

Barratt-Boyes, SM ^{[1
]}

Figdor, CG

机构：

[1] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Infect Dis & Microbiol, Pittsburgh, PA 15261 USA

[2] Univ Med Ctr, Nijmegen Ctr Mol Life Sci, Dept Tumor Immunol, Nijmegen, Netherlands

来源：

CYTOTHERAPY | 2004年 / 6卷 / 02期

关键词：

D O I：

10.1080/14653240410005258

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

DC-based immunotherapy has shown early promise in clinical cancer trials, and efforts are being made to determine the optimal method of delivery of cells to achieve the best outcome. While it is accepted that mature DCs are required for stimulation of tumor-specific immunity, the route and frequency of injection and the optimal number of cells needed for clinical success are issues that are still being debated. To solve these questions controlled clinical trials are needed.

引用

页码：105 / 110

页数：6

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